Table 3 Microbiological and antimicrobial data
Variable | Total (n = 398), No. (%) | Phase 1 (n = 237), No. (%) | Phase 2 (n = 161), No. (%) | P value |
|---|---|---|---|---|
Negative blood culture | 275 (69.1) | 152 (64.1) | 123 (76.4) | 0.009 |
Detected organismsa | 155 (38.9) | 83 (36.4) | 72 (50.3) | 0.008 |
 - Staphylococcal species | 88 (22.1) | 46 (35.7) | 42 (50.0) | 0.038 |
 - Streptococci | 36 (9.0) | 26 (20.2) | 10 (11.9) | 0.116 |
 - Enterococci | 16 (4.0) | 9 (3.8) | 7 (4.3) | 0.991 |
 - Gram-negative bacilli | 32 (8.0) | 22 (17.1) | 10 (11.9) | 0.304 |
 - Zoonosesb | 21 (5.3) | 18 (14.0) | 3 (3.6) | 0.009 |
 - Fungal infectionc | 32 (8.0) | 17 (7.2) | 15 (9.3) | 0.440 |
Basis of choice of antibiotics | ||||
 - Culture/Serology based | 86 (21.6) | 42 (17.7) | 44 (27.3) | 0.022 |
 - Empirical | 312 (78.4) | 195 (82.3) | 117 (72.7) | |
Therapeutic antibiotics usedd | (n = 1044) | (n = 610) | (n = 434) | Â |
 - Anti-Staphylococcale | 228 (21.8) | 120 (19.7) | 108 (24.9) | 0.045 |
 - Aminoglycosides | 310 (29.7) | 162 (26.6) | 148 (34.1) | 0.009 |
 - Quinolones | 20 (1.9) | 3 (0.5) | 17 (3.9) | < 0.001 |
 - B-lactam and Cephalosporins | 338 (32.4) | 233 (38.2) | 105 (24.2) | < 0.001 |