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Table 2 Angiographic characteristics and treatment characteristics at first clinical ISR presentation

From: In-stent restenosis of drug-eluting stents: clinical presentation and outcomes in a real-world scenario

Parameter

Total

ACS cohort

Non-ACS cohort

P value

ISR characteristics

(n = 210)

(n = 129)

(n = 81)

 

ISR type

   

0.961

 I. Focal

134 (63.8%)

84 (65.1%)

50 (61.7%)

 

 II. Diffuse

23 (11.0%)

14 (10.9%)

9 (11.1%)

 III. Proliferative

10 (4.7%)

6 (4.7%)

4 (4.9%)

 IV. Complete

43 (20.5%)

25 (19.4%)

18 (22.2%)

ISR vessel

   

0.203

 Left anterior descending

112 (53.3%)

62 (48.1%)

50 (61.7%)

 

 Left circumflex artery

49 (23.3%)

33 (25.6%)

16 (19.8%)

 

 Right coronary artery

47 (22.4%)

32 (24.8%)

15 (18.5%)

 

 Left main

2 (1.0%)

2 (1.6%)

0 (0.0%)

 

Proximal ISR location

113 (53.8%)

68 (52.7%)

45 (55.6%)

0.776

Disease burden

(n = 191)

(n = 118)

(n = 73)

0.715

 Single-vessel disease

72 (37.7%)

42 (35.6%)

30 (41.1%)

 

 Double-vessel disease

67 (35.1%)

42 (35.6%)

25 (34.2%)

 

 Triple-vessel disease

52 (27.2%)

34 (28.8%)

18 (24.7%)

 

Treatment plan

(n = 191)

(n = 118)

(n = 73)

0.620

 Medical therapy

37 (19.4%)

24 (20.3%)

13 (17.8%)

 

 CABG

50 (26.2%)

33 (28.0%)

17 (23.3%)

 

 PCI

104 (54.5%)

61 (51.7%)

43 (58.9%)

 

Details of PCI

 Procedural success

101 (97.1%)

59 (96.7%)

42 (97.7%)

1.000

 PCI type

   

0.082

  POBA

21 (20.2%)

16 (26.2%)

5 (11.6%)

 

  DCB

11 (10.6%)

4 (6.6%)

7 (16.3%)

 

  New DES

72 (69.2%)

41 (67.2%)

31 (72.1%)

 

   No. of stents

1.14 ± 0.35

1.16 ± 0.37

1.12 ± 0.33

0.608

   Stent length

29.7 ± 11.0

32.0 ± 12.9

26.4 ± 6.4

0.045

   Stent diameter

3.03 ± 0.40

3.00 ± 0.36

3.08 ± 0.45

0.451

  Adjunct Devices

   Rotablation

2 (1.9%)

2 (3.3%)

0 (0.0%)

0.342

   Cutting or NC balloon

24 (23.1%)

13 (21.3%)

11 (25.6%)

0.390

   IVUS guidance

25 (24.0%)

13 (21.3%)

12 (27.9%)

0.292

  1. ACS acute coronary syndrome, CABG coronary artery bypass grafting, DCB drug-coated balloon, DES drug-eluting stent, IVUS intravascular ultrasound, ISR in-stent restenosis, NC non-compliant, PCI percutaneous coronary intervention, POBA plain old balloon angioplasty