Right ventricular 2D speckle-tracking echocardiography in children with osteosarcoma under chemotherapy

The Egyptian Heart Journal

Table 3 Basal characteristics, echocardiographic results, and RV 2DSTE of group 1 subgroups at 10 weeks of receiving chemotherapy

	Group 1A (N = 93) (patients with normal RV strain)	Group 1B(N = 7) (patients with decreased RV strain)	P value
Age, years	11.66 ± 2.03	14.43 ± 0.53	0.001*
Male gender, n (%)	46 (49.5%)	4 (57.1%)	0.695
BSA, m²	1.38 ± 0.08	1.50 ± 0.01	0.001*
LVEDD, cm	3.56 ± 0.25	3.64 ± 0.24	0.427
LVESD, cm	1.79 ± 0.35	1.78 ± 0.26	0.973
LVEF, %	66.65 ± 4.03	66.71 ± 1.60	0.964
LVGLS, %	− 23.93 ± 0.81	− 23.65 ± 1.15	0.393
RVGLS, %	− 24.15 ± 0.96	− 18.43 ± 0.78	0.001*
Apical RVS, %	− 24.90 ± 0.75	− 17.42 ± 0.53	0.001*
Mid RVS, %	− 24.17 ± 0.67	− 17.57 ± 0.53	0.001*
Basal RVS, %	− 24.59 ± 1.04	− 19.00 ± 0.01	0.001*
Tapse, cm	1.85 ± 0.14	1.81 ± 0.11	0.448
FAC, %	35.86 ± 0.88	35.57 ± 0.54	0.395

BSA body surface area; LVEDD left ventricular end diastolic dimension; LVESD left ventricular end systolic dimension; LVEF left ventricular ejection fraction; LVGLS left ventricular global longitudinal strain; RVGLS right ventricular global longitudinal strain; Apical, Mid and Basal RVS right ventricular strain; Tapse tricuspid annular plane systolic excursion; FAC fractional area change
* = means significant