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Table 5 Basal characteristics, echocardiographic results, and RV 2DSTE of group 1 subgroups at 29 weeks of receiving chemotherapy

From: Right ventricular 2D speckle-tracking echocardiography in children with osteosarcoma under chemotherapy

 Group 1A (N = 88) (patients with normal RV strain)Group 1B (N = 12) (patients with decreased RV strain)P value
Age, years11.48 ± 1.9414.58 ± 0.510.001*
Male gender, n (%)45 (51.1%)5 (41.7%)0.538
BSA, m21.38 ± 0.071.48 ± 0.020.001*
LVEDD, cm3.61 ± 0.303.62 ± 0.220.930
LVESD, cm1.96 ± 0.571.87 ± 0.370.609
LVEF, %64.00 ± 7.5565.75 ± 1.350.427
LVGLS, %− 23.85 ± 0.89− 23.43 ± 1.130.142
RVGLS, %− 24.27 ± 0.83− 15.25 ± 1.860.001*
Apical RVS, %− 24.89 ± 0.77− 14.01 ± 3.130.001*
Mid RVS, %− 24.24 ± 0.63− 16.33 ± 2.500.001*
Basal RVS, %− 24.62 ± 1.06− 16.33 ± 2.460.001*
Tapse, cm1.85 ± 0.141.47 ± 0.080.001*
FAC, %35.89 ± 0.8932.42 ± 2.270.001*
  1. BSA body surface area; LVEDD left ventricular end diastolic dimension; LVESD left ventricular end systolic dimension; LVEF left ventricular ejection fraction; LVGLS left ventricular global longitudinal strain; RVGLS right ventricular global longitudinal strain; Apical, Mid and Basal RVS right ventricular strain; Tapse tricuspid annular plane systolic excursion; FAC fractional area change
  2. * = means significant