Right ventricular 2D speckle-tracking echocardiography in children with osteosarcoma under chemotherapy

The Egyptian Heart Journal

Table 5 Basal characteristics, echocardiographic results, and RV 2DSTE of group 1 subgroups at 29 weeks of receiving chemotherapy

	Group 1A (N = 88) (patients with normal RV strain)	Group 1B (N = 12) (patients with decreased RV strain)	P value
Age, years	11.48 ± 1.94	14.58 ± 0.51	0.001*
Male gender, n (%)	45 (51.1%)	5 (41.7%)	0.538
BSA, m²	1.38 ± 0.07	1.48 ± 0.02	0.001*
LVEDD, cm	3.61 ± 0.30	3.62 ± 0.22	0.930
LVESD, cm	1.96 ± 0.57	1.87 ± 0.37	0.609
LVEF, %	64.00 ± 7.55	65.75 ± 1.35	0.427
LVGLS, %	− 23.85 ± 0.89	− 23.43 ± 1.13	0.142
RVGLS, %	− 24.27 ± 0.83	− 15.25 ± 1.86	0.001*
Apical RVS, %	− 24.89 ± 0.77	− 14.01 ± 3.13	0.001*
Mid RVS, %	− 24.24 ± 0.63	− 16.33 ± 2.50	0.001*
Basal RVS, %	− 24.62 ± 1.06	− 16.33 ± 2.46	0.001*
Tapse, cm	1.85 ± 0.14	1.47 ± 0.08	0.001*
FAC, %	35.89 ± 0.89	32.42 ± 2.27	0.001*

BSA body surface area; LVEDD left ventricular end diastolic dimension; LVESD left ventricular end systolic dimension; LVEF left ventricular ejection fraction; LVGLS left ventricular global longitudinal strain; RVGLS right ventricular global longitudinal strain; Apical, Mid and Basal RVS right ventricular strain; Tapse tricuspid annular plane systolic excursion; FAC fractional area change
* = means significant