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Table 6 Basal characteristics, echocardiographic results, and RV 2DSTE of group 1 subgroups after 3 months of follow-up after receiving chemotherapy

From: Right ventricular 2D speckle-tracking echocardiography in children with osteosarcoma under chemotherapy

 

Group 1A (N = 96) (patients with normal RV strain)

Group 1B (N = 4) (patients with decreased RV strain)

P value

Age, years

11.73 ± 2.04

14.75 ± 0.50

0.004*

Male gender, n %

49 (51.0%)

1 (25.0%)

0.307

BSA, m2

1.39 ± 0.07

1.50 ± 0.01

0.006*

LVEDD, cm

3.63 ± 0.30

3.75 ± 0.28

0.449

LVESD, cm

1.96 ± 0.55

1.62 ± 0.25

0.229

LVEF, %

64.31 ± 7.31

65.75 ± 1.50

0.697

LVGLS, %

− 23.84 ± 0.88

− 23.40 ± 1.61

0.339

RVGLS, %

− 24.18 ± 0.91

− 14.25 ± 0.50

0.001*

Apical RVS, %

− 24.81 ± 1.02

− 12.01 ± 0.01

0.001*

Mid RVS, %

− 24.16 ± 0.67

− 14.75 ± 0.50

0.001*

Basal RVS, %

− 24.59 ± 1.03

− 14.50 ± 1.01

0.001*

Tapse, cm

1.83 ± 0.16

1.45 ± 0.05

0.001*

FAC, %

35.85 ± 0.87

31.00 ± 1.15

0.001*

  1. BSA body surface area; LVEDD left ventricular end diastolic dimension; LVESD left ventricular end systolic dimension; LVEF left ventricular ejection fraction; LVGLS left ventricular global longitudinal strain; RVGLS right ventricular global longitudinal strain; Apical, Mid and Basal RVS right ventricular strain; Tapse tricuspid annular plane systolic excursion; FAC fractional area change
  2. * = means significant