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Table 6 Basal characteristics, echocardiographic results, and RV 2DSTE of group 1 subgroups after 3 months of follow-up after receiving chemotherapy

From: Right ventricular 2D speckle-tracking echocardiography in children with osteosarcoma under chemotherapy

 Group 1A (N = 96) (patients with normal RV strain)Group 1B (N = 4) (patients with decreased RV strain)P value
Age, years11.73 ± 2.0414.75 ± 0.500.004*
Male gender, n %49 (51.0%)1 (25.0%)0.307
BSA, m21.39 ± 0.071.50 ± 0.010.006*
LVEDD, cm3.63 ± 0.303.75 ± 0.280.449
LVESD, cm1.96 ± 0.551.62 ± 0.250.229
LVEF, %64.31 ± 7.3165.75 ± 1.500.697
LVGLS, %− 23.84 ± 0.88− 23.40 ± 1.610.339
RVGLS, %− 24.18 ± 0.91− 14.25 ± 0.500.001*
Apical RVS, %− 24.81 ± 1.02− 12.01 ± 0.010.001*
Mid RVS, %− 24.16 ± 0.67− 14.75 ± 0.500.001*
Basal RVS, %− 24.59 ± 1.03− 14.50 ± 1.010.001*
Tapse, cm1.83 ± 0.161.45 ± 0.050.001*
FAC, %35.85 ± 0.8731.00 ± 1.150.001*
  1. BSA body surface area; LVEDD left ventricular end diastolic dimension; LVESD left ventricular end systolic dimension; LVEF left ventricular ejection fraction; LVGLS left ventricular global longitudinal strain; RVGLS right ventricular global longitudinal strain; Apical, Mid and Basal RVS right ventricular strain; Tapse tricuspid annular plane systolic excursion; FAC fractional area change
  2. * = means significant