Table 14 Summary of results of SPECT-MPI versus IFR side by side
| Â | SPECT-MPI | IFR |
|---|---|---|
Nature of the test | Non-invasive imaging | Invasive |
Pearson correlation to FFR | Strong negative correlation (− 0.704) | Strong positive correlation (0.947) |
Kappa agreement to FFR | 0.754 | 0.918 |
Overall agreement to FFR | 88% | 96% |
Sensitivity | 81.8% | 90.9% |
Specificity | 92.9% | 100% |
Positive predictive value (PPV) | 90% | 100% |
Negative predictive value (NPV) | 86.7% | 93.3% |
Positive likelihood ratio (PLR) | 11.45 | Cannot be calculated |
Negative likelihood ratio (NLR) | 0.20 | 0.09 |
Area under ROC curve | 0.899 | 1.000 |
Expected cut-off by ROC curve | Defect size > 5% | > 0.85 |