Table 2 Demographic data of patients on VA-ECMO
Studied parameters | All patients (67), N (%) | CNS events (38), N (%) | No CNS events (29), N (%) | p value | Ischaemic stroke (n = 10), N (%) | ICH (n = 8), N (%) | p value | |
|---|---|---|---|---|---|---|---|---|
Age (years) | 40.13 ± 14.2 | 40.84 ± 15.9 | 39.21 ± 11.67 | 0.032 | 44.9 ± 15.1 | 32.25 ± 11.8 | 0.01 | |
Sex | Males | 49 (73.2) | 28 (73.7) | 21 (72.4) | 0.56 | 5 (50) | 5 (62.5) | 0.32 |
Females | 18 (26.8) | 10 (26.3) | 8 (27.6) | 5 (50) | 3 (37.5) | |||
BMI | 25.97 ± 7.25 | 25 ± 7.23 | 27.24 ± 7.21 | 0.65 | 28.30 ± 7.2 | 21.38 ± 4.8 | 0.03 | |
Diabetes mellitus | 12 (17.9) | 7 (18.4) | 5 (17.2) | 0.83 | 4 (40) | 0 | 0.02 | |
Systemic hypertension | 19 (28.4) | 12 (31.6) | 7 (24.1) | 0.59 | 4 (40) | 1 (12.5) | 0.07 | |
Chronic kidney disease | 14 (20.9) | 11 (28.) | 3 (10.3) | 0.08 | 3 (30) | 2 (25) | 0.52 | |
History of stroke | 3 (4.47) | 3 (7.9) | 0 | 0.17 | 0 | 2 (25) | 0.16 | |
History of epilepsy | 1 (1.49) | 1 (2.63) | 0 | 0.29 | 0 | 1 (12.5) | 0.24 | |
Left ventricle EF | 33.63 ± 13.84 % | 33.76 ± 13.29 | 33.45 ± 14.76 | 0.17 | 37.40 ± 13.8 | 36.75 ± 16.1 | 0.19 | |
Pre-ECMO AF | 25 (37.3) | 15 (39.5) | 10 (34.5) | 0.8 | 2 (20) | 5 (62.5) | 0.04 | |
History of oral anticoagulants | 27 (40.3%) | 15 (39.5) | 12 (41.4) | 0.56 | 3 (30) | 4 (50) | 0.07 | |
Cardiothoracic surgery | 44 (65.7%) | 28 (73.6) | 16 (55.2) | 0.12 | 6 (60) | 7 (87.5) | 0.04 | |
Cardiopulmonary bypass time (minutes) | 229.9 ± 97.1 | 245.1 ± 105.6 | 203.1 ± 75.75 | 0.16 | 180.40 ± 117.13 | 250.5 ± 89.7 | 0.01 | |
Aortic clamping time (minutes) | 149.53 ± 56.46 | 154.75 ± 58.57 | 139.08 ± 52.84 | 0.42 | 129.00 ± 80.72 | 173.4 ± 53.6 | 0.03 | |
IABP | 13 (19.4) | 9 (23.7) | 4 (15.4) | 0.24 | 4 (40) | 1 (12.5) | 0.03 | |
SOFA score at admission | 13.10 ± 3.52 | 14.34 ± 2.95 | 11.48 ± 3.59 | 0.001 | 13.00 ± 3.49 | 15.25 ± 1.8 | 0.001 | |
SOFA score after 48 hours | 14.61 ± 5.82 | 16.82 ± 4.93 | 11.72 ± 5.73 | 0.001 | 15.20 ± 5.69 | 18.25 ± 4.1 | 0.001 | |
Type of ECMO | Central | 35 (52.2) | 22 (57.9) | 13 (44.8) | 0.33 | 5 (50) | 6 (75) | 0.04 |
Peripheral | 32 (47.8) | 16 (42.1) | 16 (55.2) | 5 (50) | 2 (25) | |||
Days before event | – | 10.21 ± 5.7 | – | – | 9.40 ± 5.19 | 11.13 ± 7.1 | 0.21 | |
AF during ECMO | 36 (53.7) | 26 (68.4) | 10 (34.5) | 0.007 | 8 (80) | 5 (62.5) | 0.03 | |
Intracardiac thrombi | 6 (8.9) | 5 (13.2) | 1 (3.4) | 0.2 | 4 (40) | 0 | 0.04 | |
ECMO circuit thrombi | 4 (5.9) | 3 (7.9) | 1 (3.4) | 0.4 | 1 (10) | 0 | 0.6 | |