Table 1 Demographic, clinical, and biochemical characteristics of the subjects

Male/female number

11/14

15/10

12/13

AGE (years)

56.00 ± 8.55

52.95 ± 12.61

55.80 ± 9.40

0.55

BMI (kg/m²)

25.35 ± 6.92

28.12 ± 6.52

27.37 ± 5.32

0.28

SBP (mmHg)

121.36 ± 5.15

161.75 ± 15.49

168.68 ± 7.17

< 0.001*

DBP (mmHg)

82.36 ± 3.63

102.50 ± 5.50

89.20 ± 2.55

< 0.001*

PP (mmHg)

39.00 ± 5.90

59.25 ± 13.40

79.48 ± 7.14

< 0.001*

Progranulin (ng/ml)

50.10 ± 4.70

71.36 ± 18.36

82.31 ± 16.32

< 0.001*

0.009^

TNF-α (pg/ml)

3.57 ± 1.90

19.68 ± 5.19

21.07 ± 6.32

< 0.001*

0.31^

PGRN/TNF-α ratio

23.98 ± 7.44

3.79 ± 1.33

4.32 ± 1.80

< 0.01*

0.67^