Estimated glomerular filtration rate as one of the main predictors of in-hospital mortality in Egyptian patients with ST elevation myocardial infarction: a two-year retrospective study

Wadie, Moheb; Samaan, Emad; Nassar, Mohammed Kamal; Abdelsalam, Mostafa

doi:10.1186/s43044-020-00067-z

The Egyptian Heart Journal

Table 2 Characteristics of the cohort compared according to eGFR levels

From: Estimated glomerular filtration rate as one of the main predictors of in-hospital mortality in Egyptian patients with ST elevation myocardial infarction: a two-year retrospective study

Parameter	Group 1 (eGFR ≥ 60 ml/min/1.73 m²)	Group 2 (eGFR < 60 ml/min/1.73 m²)	P
Number (n) (%)	354 (78.6%)	96 (21.4%)
Age (years)	54.79 ± 10.4	64.94 ± 9.16	< 0.0001**
Gender
Male	305 (86.2%)	68 (70.8%)	< 0.0001**
Female	49 (13.8%)	28 (29.2%)
Smoking	216 (61%)	40 (41.7%)	0.001*
Diabetes mellitus	141 (39.8%)	51 (53.1%)	0.01*
Hypertension	122 (34.5%)	55 (57.3%)	< 0.0001**
BMI (kg/m²)	29.17 ± 4.99	30.16 ± 5.72	0.12
AF	9 (2.5%)	9 (9.4%)	0.002*
PVD	1 (0.3%)	2 (2.1%)	0.054
CHF	1 (0.3%)	2 (2.1%)	0.054
Thyroid illness	2 (0.6%)	2 (2%)	0.13
Malignancy	3 (0.8%)	4 (4.2%)	0.02*
Hemodialysis	0	2 (2.1%)	0.006*
Sleep apnea	1 (0.3%)	0	0.6
Previous MI	16 (4.5%)	8 (8.3%)	0.14
Previous angina	43 (12.1%)	15 (15.6%)	0.36
Previous PCI	12 (3.4%)	4 (4.2%)	0.71
Previous CABG	3 (0.8%)	0	0.36
Previous stroke	18 (5.1%)	7 (7.3%)	0.4
Admission duration (days)	4 (1–13)	4 (1–11)	0.86
Baseline clinical and laboratory data on admission
HR (beats/minute)	82.92 ± 19.12	81.66 ± 25.21	0.64
SBP (mmHg)	120.36 ± 24.17	117.08 ± 31.31	0.34
DBP (mmHg)	76.17 ± 13.96	72.7 ± 18.55	0.04*
MSI	0.94 ± 0.32	1 ± 0.46	0.16
Ejection fraction (%)	51.34 ± 9.2	49.15 ± 10.41	0.06
RSWMA	294 (83.1%)	80 (83.3%)	0.63
Creatinine (mg/dl)	0.9 (0.6–1.2)	1.5 (0.7–7.2)	< 0.0001**
eGFR (ml/min/1.73 m²)	91.5 ± 17.98	42.88 ± 13.55	< 0.0001**
RBS (mg/dl)	177.41 ± 75.68	225.05 ± 109.1	< 0.0001**
HbA1c (%)	8.76 ± 2.57	8.95 ± 2.74	0.86
Uric acid (mg/dl)	5.85 ± 1.73	7.94 ± 2.05	0.0001**
Hemoglobin (gm/dl)	13.99 ± 1.74	13.4 ± 1.98	0.005*
*Neutrophil10**³	8.5 (0.62–26.5)	8.9 (0.9–26)	0.62
*Lymphocyte10**³	2.1 (0.39–19.4)	1.7 (0.29–17.23)	0.17
Nutrophil/lymphocyte ratio (NLR)	2.8 (0.52–17.2)	2.67 (0.6–4.74)	0.55
*Platelets10**³	241 (66–574)	216 (32–752)	0.08
CK-MB (IU/L)	60 (12–1150)	80.5 (1–876)	0.03*
Positive troponin (qualitative test)	183 (51.7%)	67 (69.8%)	0.001*
Total cholesterol (mg/dl)	203.41 ± 50.86	185.43 ± 41.4	0.004*
LDL-cholestrol (mg/dl)	130.7 ± 37.51	112.43 ± 34.11	0.008*
HDL-cholesterol (mg/dl)	43.92 ± 16.11	46 ± 17.3	0.8
Triglycerides (mg/dl)	144 (35–711)	134.5 (60–792)	0.15

Data expressed as mean ± SD, median (min-max), or number (%)
BMI body mass index, AF atrial fibrillation, PVD peripheral vascular disease, CHF congestive heart failure, MI myocardial infarction, PCI percutaneous coronary intervention, CABG coronary artery bypass grafting, HR heart rate, SBP systolic blood pressure, DBP diastolic blood pressure, MSI modified shock index, RSMWA resting segmental wall motion abnormalities, eGFR estimated glomerular filtration rate, RBS random blood sugar, LDL low-density lipoprotein, HDL high-density lipoprotein
*P < 0.05
**P < 0.0001

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