Colchicine ameliorates the chronic inflammatory state in patients with chronic rheumatic valvular heart disease: a pilot study

The Egyptian Heart Journal

Table 1 Baseline data of patient and control groups before receiving colchicine

		Control group	Patients group	Test value	P-value	Sig.
		No. = 10	No. = 35	Test value	P-value	Sig.
Age (years)	Mean ± SD	31.70 ± 2.98	33.77 ± 4.83	− 1.283	0.206	NS
Age (years)	Range	29 – 38	28 – 54	− 1.283	0.206	NS
Gender	Female	5 (50.0%)	24 (68.6%)	1.171	0.279	NS
Gender	Male	5 (50.0%)	11 (31.4%)	1.171	0.279	NS
CRP level (IU/ml)	Mean ± SD	0 ± 0	6.09 ± 4.39	− 4.343	0.0001	HS
CRP level (IU/ml)	Range	0–0	0–12	− 4.343	0.0001	HS
IL-6 level (ng/L)	Mean ± SD	10.50 ± 5.99	113.57 ± 37.41	− 8.612	0.0001	HS
IL-6 level (ng/L)	Range	5–20	30–160	− 8.612	0.0001	HS

SD standard deviation, CRP C-reactive protein, IL-6 interleukin-6, NS non-significant, HS highly significant