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Table 1 Demographic, clinical characteristics, and laboratory data of the patients with and without aortic root abscess, median ± IQR or N (%)

From: Prevalence and predictors of aortic root abscess among patients with left-sided infective endocarditis: a cross-sectional comparative study

  ARA (N = 61) NO-ARA (N = 224) p value
Age 31 (24, 40.5) 32 (24,43) 0.36
Male gender 42 (68.9%) 122 (54.5%) 0.04
Underlying cardiac conditions
 RHD 27 (45.0%) 121 (54.3%) 0.20
 Mechanical prosthesis 31 (50.8%) 40 (17.9%) < 0.001
 Congenital heart disease 11 (18.3%) 16 (7.1%) 0.009
 Bicuspid aortic valve 8 (13.1%) 9 (4.0%) 0.01
 Prior IE 8 (13.3%) 8 (3.6%) 0.008
 Degenerative heart disease 4 (6.6%) 23 (10.4%) 0.37
 IV drug abuse 0 (0%) 7 (3.1%) 0.35
 Normal Heart 1 (1.6%) 17 (7.6%) 0.14
Comorbidities
 DM 6 (9.8%) 15 (6.7%) 0.41
 CKD 4 (6.6%) 22 (9.8%) 0.43
 Hemodialysis 3 (4.9%) 8 (3.6%) 0.70
 Chronic steroid use 0 (0%) 12 (5.4%) 0.08
 Chronic hepatic disease 1 (1.6%) 10 (4.5%) 0.47
 Collagen vascular disease 0 (0%) 6 (6.7%) 0.35
Clinical manifestations
 Duration of symptoms (Days) 30 (14, 90) 28 (14, 84) 0.77
 Temperature (Celsius) 38 (37, 39) 38 (37.5, 39) 0.82
 Heart rate (bpm) 100 (96,120) 100 (90,110) 0.11
Laboratory data
 Anemia 52 (94.5%) 199 (93.9%) 0.999
 Minimum Hemoglobin (gm/dL). 8.9 (7.5, 10) 9.0 (7.7, 10.2) 0.61
 Leukocytosis 39 (68.4%) 137 (65.2%) 0.65
 TLC (*103/cc) 13 (10.1, 17.3) 13 (9, 18.4) 0.96
 Initial Creatinine (mg/dl) 0.9 (0.7, 1.2) 0.9 (0.7, 1.2) 0.87
 CRP (mg/L) 120 (48, 183) 77 (37, 130) 0.03
 Antibiotic use before referral 67.8% 70.5% 0.69
 Surgical management 44(73.3%) 121(66.5%) 0.32
  1. ARA aortic root abscess, CKD chronic kidney disease, CRP C-reactive protein, DM diabetes mellitus, IE infective endocarditis, RHD rheumatic heart disease, TLC total leucocytic count