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Table 3 Standard transthoracic echocardiographic measurements at baseline, 24 h and 1 month post-ASD closure

From: The changes in biventricular remodelling and function after atrial septal defect device closure and its relation to age of closure

Basic parameters

Pre-closure

Post-closure 1

Post-closure 2

Pvalue1

Pvalue2

Pvalue3

LAD (cm)

2.85 ± 0.13

2.83 ± 0.12

3.06 ± 0.12

0.701

0.690

0.960

LVEDD (cm)

3.55 ± 0.13

3.71 ± 0.13

4.15 ± 0.13

0.039

0.001

0.017

RVEDD (cm)

3.07 ± 0.12

2.75 ± 0.12

2.53 ± 0.13

< 0.001

< 0.001

< 0.001

RVEDD/LVEDD (cm)

0.88 ± 0.03

0.75 ± 0.02

0.60 ± 0.02

0.003

< 0.001

< 0.001

Septal e′ (cm/s)

11.42 ± 0.37

9.66 ± 0.34

9.15 ± 0.49

< 0.001

0.002

0.950

TAPSE (cm)

2.74 ± 0.08

2.48 ± 0.07

3.19 ± 0.50

0.003

0.420

0.210

RVSP (mmHg)

30.36 ± 1.38

23.94 ± 1.03

23.22 ± 1.16

< 0.001

< 0.001

0.110

Qp/Qs

2.83 ± 0.16

0.88 ± 0.01

0.88 ± 0.02

< 0.001

< 0.001

0.58

  1. Pvalue1: ASD data (24 h after closure) in comparison with Pre-closure
  2. Pvalue2: ASD data (1 month after closure) in comparison with Pre-closure
  3. Pvalue3: ASD data (1 month after closure) in comparison with 24 h after closure
  4. Continues data were presented as mean ± SE. P < 0.05 was considered significant, and < 0.001 was considered highly significant. Paired two-tailed t test was used for comparison between the different stages
  5. Pre-closure before ASD device closure, Post-closure 1 1 day after ASD device closure, Post-closure 2 1 month after the intervention, LAD left atrial diameter, LVEDD left ventricular end-diastolic diameter, RVEDD right ventricular end-diastolic diameter, Septal e′ early diastolic velocity of septal mitral annulus motion, TAPSE tricuspid annular plane systolic excursion, RVSP right ventricular systolic pressure, Qp/Qs systemic/pulmonary blood flow