Basic parameters | Pre-closure | Post-closure 1 | Post-closure 2 | Pvalue1 | Pvalue2 | Pvalue3 |
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LAD (cm) | 2.85 ± 0.13 | 2.83 ± 0.12 | 3.06 ± 0.12 | 0.701 | 0.690 | 0.960 |
LVEDD (cm) | 3.55 ± 0.13 | 3.71 ± 0.13 | 4.15 ± 0.13 | 0.039 | 0.001 | 0.017 |
RVEDD (cm) | 3.07 ± 0.12 | 2.75 ± 0.12 | 2.53 ± 0.13 | < 0.001 | < 0.001 | < 0.001 |
RVEDD/LVEDD (cm) | 0.88 ± 0.03 | 0.75 ± 0.02 | 0.60 ± 0.02 | 0.003 | < 0.001 | < 0.001 |
Septal e′ (cm/s) | 11.42 ± 0.37 | 9.66 ± 0.34 | 9.15 ± 0.49 | < 0.001 | 0.002 | 0.950 |
TAPSE (cm) | 2.74 ± 0.08 | 2.48 ± 0.07 | 3.19 ± 0.50 | 0.003 | 0.420 | 0.210 |
RVSP (mmHg) | 30.36 ± 1.38 | 23.94 ± 1.03 | 23.22 ± 1.16 | < 0.001 | < 0.001 | 0.110 |
Qp/Qs | 2.83 ± 0.16 | 0.88 ± 0.01 | 0.88 ± 0.02 | < 0.001 | < 0.001 | 0.58 |
- Pvalue1: ASD data (24 h after closure) in comparison with Pre-closure
- Pvalue2: ASD data (1 month after closure) in comparison with Pre-closure
- Pvalue3: ASD data (1 month after closure) in comparison with 24 h after closure
- Continues data were presented as mean ± SE. P < 0.05 was considered significant, and < 0.001 was considered highly significant. Paired two-tailed t test was used for comparison between the different stages
- Pre-closure before ASD device closure, Post-closure 1 1 day after ASD device closure, Post-closure 2 1 month after the intervention, LAD left atrial diameter, LVEDD left ventricular end-diastolic diameter, RVEDD right ventricular end-diastolic diameter, Septal e′ early diastolic velocity of septal mitral annulus motion, TAPSE tricuspid annular plane systolic excursion, RVSP right ventricular systolic pressure, Qp/Qs systemic/pulmonary blood flow