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Table 3 Comparing ECG and echocardiographic variables in patients with liver cirrhosis before and after treatment

From: Effect of direct-acting antivirals on corrected QT interval and cardiac functions in patients with chronic hepatitis C virus infection

Variable

Before treatment (n = 50)

After treatment (n = 50)

p value

QTc, ms

415.84 ± 24.40

410.96 ± 29.41

0.48

LVEDD, mm

48.14 ± 2.81

49.3 ± 2.33

0.26

LVESD, mm

29.8 ± 2.44

30.18 ± 2.04

0.701

LVEDV, ml

94.96 ± 18.67

96.84 ± 17.71

0.183

LVESV, ml

31.16 ± 6.51

31.92 ± 5.32

0.359

LVEDVI, ml/m2

52.98 ± 9.08

54.14 ± 9.59

0.133

LVESVI, ml/m2

17.4 ± 3.01

17.82 ± 2.8

0.354

LVEF, %

66.04 ± 2.98

65.42 ± 4.9

0.41

LAVI, ml/m2

25.96 ± 3.96

26.86 ± 4.12

0.032

Trans-mitral E/A ratio

1.09 ± 0.38

1.1 ± 0.36

0.678

DT, ms

182.36 ± 30.85

180.98 ± 21.85

0.751

Lateral mitral E’, cm/s

14.38 ± 3.59

13.62 ± 3.21

0.02

E/E’ ratio

6.77 ± 2.44

6.61 ± 2.22

0.62

RVSP, mmHg

26.34 ± 6.06

27.54 ± 7.15

0.131

Mean PAP, mmHg

16 ± 3.1

16.86 ± 3.47

0.097

TAPSE, mm

24.56 ± 3.08

23.94 ± 2.8

0.164

RVFAC, %

45.72 ± 4.88

44.98 ± 4.86

0.149

LV GLS

−20 (−26 – −16.5)

− 20 (−24 – − 16)

0.198

RV GLS

−22 (−30 – −17)

−21 (− 30 – − 16)

0.122

  1. Continuous variables for variables that passed normality tests are expressed as mean and standard deviation while for those that did not pass normality test as median (range).QTc indicated corrected QT interval, LVEDD indicates left ventricular end-diastolic dimension, LVESD indicates left ventricular end-systolic dimension, LVEDV indicates left ventricular end-diastolic volume, LVESV indicates left ventricular end-systolic volume, LVEDVI indicates indexed left ventricular end-diastolic volume, indexed LVESVI indicates left ventricular end-systolic volume, LVEF indicates left ventricular ejection fraction, LAVI indicated indexed left atrial volume, RVSP indicated right ventricular systolic pressure, PAP indicated pulmonary artery pressure, TAPSE indicates tricuspid annular plane systolic excursion, RVFAC indicates right ventricular fractional area change, LV GLS indicates left ventricular global longitudinal strain, RV GLS indicates right ventricular global longitudinal strain