Table 5 Association between TGF β1 rs1800470 genotype/alleles and clinical/hematological parameters in study groups
Parameters | Groups | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
CAE patient group | Control group | |||||||||
rs1800470 genotype | rs1800470 alleles | rs1800470 genotype | rs1800470 alleles | |||||||
AA (n=23) | GG (n=10) | AG (n=23) | A Allele (n=46) | G Allele (n=33) | AA (n=13) | GG (n=8) | AG (n=23) | A Allele (n=36) | G Allele (n=31) | |
Age (years) | 63.52±2.10 | 61.60±3.25 | 61.22±1.89 | 62.37±1.41 | 61.33±1.61 | 58.38±3.36 | 64.25±1.83 | 59.35±2.79 | 59.00±2.13 | 60.61±2.14 |
TGFβ1 (ng/ml) | 2691.90±330.47 p= 0.030 | 3592.50±351.49 | 3700.00±333.25 | 3183.65±245.05 | 3669.28±255.07 p=0.012 | 4293.63±998.47 p= 0.030 | 4796.66±589.16 | 5255.00±951.77 | 4863.33±688.84 | 5130.00±703.63 |
Fasting glucose (mg/dl) | 117.91±7.07 | 123.70±18.14 | 118.61±10.36 | 118.26±6.20 | 120.15±8.92 | 130.46±19.803 | 101.25±7.95 | 129.00±15.96 | 129.53±12.29 | 121.84±12.14 |
HbA1c (%) | 6.32±0.16 | 6.99±0.82 | 6.47±0.21 | 6.40±0.13 | 6.63±0.28 | 6.44±0.35 | 5.79±0.16 | 6.13±0.16 | 6.24±0.16 | 6.04±0.12 |
ALT (U/L) | 24.52±6.26 | 23.20±3.45 | 32.17±5.57 | 28.35±4.18 | 29.45±4.05 | 26.31±6.53 | 27.88±5.53 | 18.52±1.23 | 21.33±2.50 | 20.94±1.79 |
AST (U/L) | 22.96±3.93 | 18.70±1.49 | 28.13±3.78 | 25.54±2.72 | 25.27±2.76 | 23.69±5.75 | 23.88±1.72 | 19.83±1.73 | 21.22±2.32 | 20.87±1.38 |
BUN (mg/dl) | 16.00±0.84 | 15.80±1.28 | 15.65±0.79 | 15.83±0.57 | 15.70±0.66 | 18.15±1.70 | 18.13±1.85 | 15.61±1.55 | 16.53±1.17 | 16.26±1.25 |
Creatine (mg/dl) | 0.85±0.04 | 0.99±0.10 | 0.96±0.05 | 0.90±0.03 | 0.96±0.04 | 0.91±0.06 | 0.91±0.12 | 0.82±0.04 | 0.85±0.04 | 0.84±0.04 |
WBC (103μl) | 8.50±0.49 | 8.80±1.01 | 8.23±0.56 | 8.37±0.37 | 8.40±0.49 | 7.50±0.48 | 7.65±0.98 | 8.27±0.58 | 7.99±0.41 | 8.11±0.49 |
Platelet (103μl) | 244.22±15.99 | 197.19±20.52 | 252.30±11.68 | 248.26±9.81 p= 0.018 | 235.82±10.99 | 247.15±20.09 | 249.38±30.67 | 251.74±13.50 | 250.08±11.11 | 251.13±12.48 |