Efficacy and safety of hydro-mechanical defragmentation in intermediate- and high-risk pulmonary embolism

The Egyptian Heart Journal

Table 1 Clinical, demographic and investigational characteristics of the study groups

Characteristics	Group A (HMD)	Group B (ST)	p value
Characteristics	No. 25	No. 25	p value
Age (range) year	49.6 ± 13.13 (26–68)	42.92 ± 12.3 (28–80)	0.070
Female gender (%)	13 (52%)	17 (68%)	0.248
Risk factor for pulmonary embolism
Major surgery	6 (24%)	10 (40%)	0.363
Fracture	6 (24%)	3 (12%)	0.462
Cancer	3 (12%)	1 (4%)	0.602
Paraplegia	1 (4%)	0 (0%)	1.000
Contraceptive pills	3 (12%)	4 (16%)	1.000
Stroke	0 (0%)	2 (8%)	0.470
Unknown	6 (24%)	5 (20%)	1.000
CTPA results on admission (%)
Bilateral main PE	21 (84%)	17 (68%)	0.069
Saddle shaped PE	4 (16%)	2 (8%)
Right main PE	0	4 (16%)
Left main PE	0	2 (8%)
Echocardiography (%)			0.97
Dilated right side	25 (100%)	25 (100%)	0.069
60/60 sign	25 (100%)	25 (100%)
McConnell sign	25 (100%)	25 (100%)
Type of pulmonary embolism(%)
High-risk PE	17 (68%)	17 (68%)	0.989
Intermediate-high-risk PE	8 (32%)	8 (32%)	0.989
Procedure done (%)
Fragmentation only	10 (40%)	0
Fragmentation and local thrombolysis	9 (36%)	0
Fragmentation and local thrombolysis after failure of ST	6 (24%)	0

Data are presented as mean ± standard deviation or number and percent. HMD = hydro-mechanical defragmentation; ST = systemic thrombolysis; PE = pulmonary embolism; CTPA = computed tomography pulmonary angiography; yr. = years
*Statistically significant difference (p < 0.05); **Highly statistically significant difference (p < 0.01)