Efficacy and safety of hydro-mechanical defragmentation in intermediate- and high-risk pulmonary embolism

The Egyptian Heart Journal

Table 2 Efficacy parameters of the study groups comparing admission and follow-up results

	Group A (HMD)	Group B (ST)	p value
	No. 25	No. 25	p value
Systolic blood pressure
Before procedure	87.2 ± 17.68	85.2 ± 7.14	0.602
After 24 h	98.75 ± 16.24	89.2 ± 12.22	0.024
After 48 h	108.7 ± 10.14	94.09 ± 11.82	< 0.001**
After 30 day	119 ± 6.41	109.47 ± 18.1	0.033*
Diastolic blood pressure
Before procedure	53.2 ± 16	52.8 ± 7.92	0.911
After 24 h	63.75 ± 9.24	55.6 ± 8.7	0.003**
After 48 h	68.7 ± 7.57	59.55 ± 7.22	< 0.001**
After 30 day	76 ± 5.03	70 ± 12.47	0.054
Pulmonary artery systolic pressure
Before procedure	59.68 ± 8.35	52.2 ± 6.63	< 0.001**
After 48 h	46.1 ± 12.18	48.67 ± 6.4	0.464
After 30 day	36.5 ± 10.35	42.24 ± 6.6	0.065
Respiratory rate
Before procedure	37.68 ± 4.29	36.8 ± 6.79	0.586
After 24 h	30.79 ± 3.91	32.28 ± 5.06	0.257
After 48 h	26.83 ± 5.08	30.73 ± 5.1	0.013*
After 30 day	19.4 ± 1.73	21.47 ± 2.29	0.004**
Oxygen saturation
Before procedure	88.44 ± 3.94	92.28 ± 2.56	< 0.001**
After 24 h	91.71 ± 3.09	92 ± 3.11	0.743
After 48 h	92.65 ± 4.77	92.82 ± 3.36	0.894
After 30 day	95.4 ± 1.14	96.47 ± 1.62	0.025*
Heart rate
Before procedure	130.8 ± 10.38	124.8 ± 8.23	0.028*
After 24 h	117.5 ± 8.97	117.6 ± 8.79	0.969
After 48 h	110 ± 7.98	110.91 ± 6.84	0.684
After 30 day	95.5 ± 5.1	93.44 ± 11.35	0.469
Shock index (HR/SBP)
Before procedure	1.54 ± 0.4	1.44 ± 0.18	0.276
After 24 h	1.21 ± 0.28	1.32 ± 0.26	0.142
After 48 h	1 ± 0.14	1.2 ± 0.24	<0.001**
After 30 day	0.78 ± 0.1	0.77 ± 0.1	0.940

Data are presented as mean ± standard deviation. HMD = hydro-mechanical defragmentation; ST = systemic thrombolysis; PE = pulmonary embolism. * Statistically significant difference (p < 0.05); ** Highly statistically significant difference (p < 0.01)