Table 1 Baseline characteristics of CAD patients under 60 years old
Study | Overall (N = 16,410) | STICH (n = 625) | LOTUS (n = 1792) | Li et al. (n = 2018) | COURAGE (n = 1381) | Rosato et al. (n = 2547) | Otten et al. (n = 3714) | Rathod et al. (n = 367) | Roth et al. (n = 2046) | Fu et al. (n = 1920) |
|---|---|---|---|---|---|---|---|---|---|---|
Age (years) | 51.2 ± 6 | 53.3 ± 6 | 47.7 ± 6 | 41.6 ± 3 | 55.5 ± 6 | 53.8 ± 4 | 54.2 ± 6 | 39.6 ± 5 | 52.0 ± 5 | 52.6 ± 7 |
Female | 2665 (16.2%) | 61 (9.8%) | 486 (27.1%) | 142 (7.0%) | 184 (13.3%) | 265 (10.4%) | 708 (19.1%) | 47 (12.8%) | 545 (26.6%) | 227 (11.8%) |
Family history | 4241/13238 (32.0%) | NA | 700 (39.1%) | 268 (13.3%) | 766 (55.5%) | NA | 1775 (47.8%) | 122 (33.2%) | 418 (20.4%) | 192 (10.0%) |
History of MI | 3160/15785 (20.0%) | 479 (76%) | 606 (33.8%) | 498 (24.7%) | 550 (39.8%) | 718 (28.2%) | 262 (7.1%) | 26 (7.1%) | 329 (16.1%) | 171 (8.9%) |
History of PCI | 1383/13863 (10.0%) | 83 (13.3%) | 236 (13.2%) | 291 (14.4%) | 214 (15.5%) | NA | 181 (4.9%) | 22 (6.0%) | 225 (11.0%) | 131 (6.8%) |
History of CABG | 329/12472 (2.6%) | 18 (2.9%) | 37 (2.1%) | NA | 111 (8.0%) | 36 (1.4%) | 67 (1.8%) | 0 (0.0%) | 60 (2.9%) | NA |
History of stroke | 493/12472 (3.9%) | 37 (5.9%) | 92 (5.1%) | 61 (3.0%) | NA | 48 (1.9%) | 67 (1.8%) | NA | NA | 188 (9.8%) |
Diabetes mellitus | 2965/14392 (20.6%) | 224 (35.8%) | 618 (34.5%) | 2018 (100%) | 456 (33.0%) | 675 (26.5%) | 305 (8.2%) | 36 (9.8%) | 301 (14.7%) | 350 (18.2%) |
Hypertension | 6604/13863 (47.6%) | 355 (56.8%) | 1116 (62.3%) | 1198 (59.4%) | 884 (64.0%) | NA | 1044 (28.1%) | 81 (22.1%) | 1027 (50.2%) | 899 (46.8%) |
Hyperlipidemia | 4122/10464 (39.4%) | 364 (58.2%) | 1091 (60.9%) | NA | NA | NA | 838 (22.6%) | 80 (21.8%) | 1171 (57.2%) | 578 (30.1%) |
Current smoker | 7548/13863 (54.4%) | 168 (26.9%) | 1033 (57.6%) | 1413 (70.0%) | 548 (39.7%) | NA | 2234 (60.2%) | 230 (62.7%) | 556 (27.2%) | 1366 (71.1%) |
BMI (kg/m2) | 27.7 ± 2.5 | 27 ± 3.5 | 26.5 ± 3.2 | 27.4 ± 3.3 | 30 ± 5.0 | NA | NA | NA | 27.7 ± 5.0 | NA |
LVEF (%) | – | 28 (22, 34) | 59.4 ± 13.1 | 59.3 ± 9.5 | 61.0 ± 11 | NA | NA | 45.3 ± 7.3 | 60 (47_69) | NA |
Special clinical characteristic | – | HF-LVSD | TVD | DM | Stable angina | NA | STEMI | STEMI | Stable angina | STEMI |
TVD | 4891/11220 (43.6%) | 360 (57.6%) | 1792 (100%) | NA | 381 (27.6%) | NA | 1578 (42.5%) | 81 (22.1%) | 393 (19.2%) | 666 (34.7%) |