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Table 1 Baseline characteristics of CAD patients under 60 years old

From: Mortality probabilities after revascularization and medical therapy in CAD patients under 60 years old: a meta-analysis study

Study Overall (N = 16,410) STICH (n = 625) LOTUS (n = 1792) Li et al. (n = 2018) COURAGE (n = 1381) Rosato et al. (n = 2547) Otten et al. (n = 3714) Rathod et al. (n = 367) Roth et al. (n = 2046) Fu et al. (n = 1920)
Age (years) 51.2 ± 6 53.3 ± 6 47.7 ± 6 41.6 ± 3 55.5 ± 6 53.8 ± 4 54.2 ± 6 39.6 ± 5 52.0 ± 5 52.6 ± 7
Female 2665 (16.2%) 61 (9.8%) 486 (27.1%) 142 (7.0%) 184 (13.3%) 265 (10.4%) 708 (19.1%) 47 (12.8%) 545 (26.6%) 227 (11.8%)
Family history 4241/13238 (32.0%) NA 700 (39.1%) 268 (13.3%) 766 (55.5%) NA 1775 (47.8%) 122 (33.2%) 418 (20.4%) 192 (10.0%)
History of MI 3160/15785 (20.0%) 479 (76%) 606 (33.8%) 498 (24.7%) 550 (39.8%) 718 (28.2%) 262 (7.1%) 26 (7.1%) 329 (16.1%) 171 (8.9%)
History of PCI 1383/13863 (10.0%) 83 (13.3%) 236 (13.2%) 291 (14.4%) 214 (15.5%) NA 181 (4.9%) 22 (6.0%) 225 (11.0%) 131 (6.8%)
History of CABG 329/12472 (2.6%) 18 (2.9%) 37 (2.1%) NA 111 (8.0%) 36 (1.4%) 67 (1.8%) 0 (0.0%) 60 (2.9%) NA
History of stroke 493/12472 (3.9%) 37 (5.9%) 92 (5.1%) 61 (3.0%) NA 48 (1.9%) 67 (1.8%) NA NA 188 (9.8%)
Diabetes mellitus 2965/14392 (20.6%) 224 (35.8%) 618 (34.5%) 2018 (100%) 456 (33.0%) 675 (26.5%) 305 (8.2%) 36 (9.8%) 301 (14.7%) 350 (18.2%)
Hypertension 6604/13863 (47.6%) 355 (56.8%) 1116 (62.3%) 1198 (59.4%) 884 (64.0%) NA 1044 (28.1%) 81 (22.1%) 1027 (50.2%) 899 (46.8%)
Hyperlipidemia 4122/10464 (39.4%) 364 (58.2%) 1091 (60.9%) NA NA NA 838 (22.6%) 80 (21.8%) 1171 (57.2%) 578 (30.1%)
Current smoker 7548/13863 (54.4%) 168 (26.9%) 1033 (57.6%) 1413 (70.0%) 548 (39.7%) NA 2234 (60.2%) 230 (62.7%) 556 (27.2%) 1366 (71.1%)
BMI (kg/m2) 27.7 ± 2.5 27 ± 3.5 26.5 ± 3.2 27.4 ± 3.3 30 ± 5.0 NA NA NA 27.7 ± 5.0 NA
LVEF (%) 28 (22, 34) 59.4 ± 13.1 59.3 ± 9.5 61.0 ± 11 NA NA 45.3 ± 7.3 60 (47_69) NA
Special clinical characteristic HF-LVSD TVD DM Stable angina NA STEMI STEMI Stable angina STEMI
TVD 4891/11220 (43.6%) 360 (57.6%) 1792 (100%) NA 381 (27.6%) NA 1578 (42.5%) 81 (22.1%) 393 (19.2%) 666 (34.7%)
  1. PCI: percutaneous coronary intervention; CABG: coronary artery bypass graft; MT: medical treatment; NA: not available; LVEF: left ventricular ejection fraction; TVD: three vessel disease; BMI: body mass index; HF-LVSD: heart failure and left ventricular systolic dysfunction; DM: diabetes mellitus; STEMI: ST-elevation myocardial infarction