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Table 1 Patient characteristics

From: C2HEST score for atrial fibrillation risk prediction models: a Diagnostic Accuracy Tests meta-analysis

Study Country Group Population Mean follow-up, years (SD) Age (years) Female (%) HTN, n
(%)
HF, n
(%)
DM, n
(%)
CAD, n
(%)
COPD, n (%) AF, n (%) Mean C2HEST
Guo et al. [30] China HHS 209,274
GP
NA 34 ± 11.30 10.6% 31,987 (15.28%) 3286 (1.57%) 7620 (3.64%) 6146 (2.94%) 68,335 (32.66%) 491 (0.23) 1 ± 0.47
Hu and Lin [24] Taiwan National cohort 692,691
GP
10.9 ± 2.74 41.3 ± 16.3 49.4% 99,794
(14.4%)
4120 (0.59%) NA 43,301
(6.25%)
25,379
(3.66%)
209
(0.03)
0.32 ± 0.79
Khurshid et al. [26] USA EHR-AF 4,508,180
GP
3.1 9 ± 1.98 62.5 ± 10.9 56.3% 2,375,811
(52.7%)
166,803
(3.7%)
978,275
(21.7%)
545,490
(12.1%)
NA 283,783
(6.3)
NA
Liag et al. [29] China TOPCAT 2202
CD
3.89 ± 0.98 67.01 ± 9.44 54.7% 2024
(91.9%)
NA 752
(34.2%)
NA 231
(10.5%)
130
(5.9)
NA
Lip et al. [16] Denmark Danish Cohort Study 2,499,235
CD
4.92 ± 1.18 65.08 ± 10.2 52.9% 611,117
(24.45%)
103,769
(4.15%)
142,507
(5.70%)
229,054
(9.16%)
108,692
(4.35%)
132,012
(5.2)
1.16 ± 1.01
Hu and Lin [27] Taiwan NHIRD 4601
CD
10.9 ± 2.74 62.6 ± 14.3 50.2% 4174 (90.7%) 1029 (22.4%) 2351 (51.1%) 2082
(45.3%)
874
(19.0%)
209
(4.5)
2.33 ± 1.55
Hulme et al. [25] USA RPDR 412,085
GP
4.92 ± 1.18 61.0 ± 11.0 58% 115,384 (28%) 12,775 (3.1%) 38,736 (9.4%) 38,324
(9.3%)
NA 29,035
(7.04)
NA
Li et al. [28] France FNS 240,459
CD
7.9 ± 11.5 70.8 ± 15.7 47% 141,045 (90.7%) 33,162 (14.7%) 50,977 (22.5%) 39,652
(17.5%)
35,320
(15.6%)
66,811
(27.7)
4.7 ± 1.99
Li et al. [15] China CYID 471,446
GP
4.1 ± 3.5 56.1 ± 9.3 46% 143,168 (31.7%) 5515
(1.2%)
37,372
(8.3%)
9946
(2.2%)
44,470
(9.9%)
921
(0.19)
0.75 ± 0.56
  1. HTN hypertension, HF heart failure, DM diabetes mellitus, CAD coronary artery disease, COPD chronic obstructive pulmonary disease, LAD left atrial diameter, LVEF left ventricular ejection fraction, ACEIs angiotensin converting enzyme inhibitors, ARBs angiotensin receptor blockers, CCB calcium channel blockers, GP general population, CD chronic diseases, RPDR Partners HealthCare System Research Patient Data Registry, FNS A French Nationwide Study, CYID Chinese Yunnan Insurance Database, AF atrial fibrillation