Table 1 Differences of the baseline parameters between PHT and non-PHT patients
Variables | All | PHT | Non-PHT | p* |
|---|---|---|---|---|
(n: 143, 100%) | (n = 73, 51%) | (n = 70, 49%) | ||
Demographic parameters | ||||
Age (years), mean ± SD | 54.2 ± 18.4 | 55.9 ± 16.2 | 52.50 ± 20.3 | 0.260 |
Male gender, n (%) | 65 (45.5) | 31 (42.5) | 34 (48.6) | 0.464 |
Age categories in years, n (%) | 0.544 | |||
14–24 | 16 (11.2) | 5 (6.8) | 11 (15.7) | |
25–34 | 8 (5.6) | 4 (5.5) | 4 (5.7) | |
35–44 | 11 (7.7) | 5 (6.8) | 6 (8.6) | |
45–54 | 28 (19.6) | 17 (23.3) | 11 (15.7) | |
55–64 | 34 (23.8) | 19 (26.0) | 15 (21.4) | |
≥ 65 | 46 (32.2) | 23 (31.5) | 23 (32.9) | |
Hypertension, n (%) | 81 (56.6) | 42 (57.5) | 39 (55.7) | 0.829 |
Diabetes mellitus, n (%) | 72 (50.3) | 42 (57.5) | 30 (42.9) | 0.079 |
Smoking, n (%) | 5 (3.5) | 3 (4.1) | 2 (2.9) | 0.684 |
BMI (km/m2), mean ± SD | 22.1 ± 2.7 | 22.3 ± 2.2 | 21.8 ± 3.1 | 0.273 |
Echocardiographic parameters | ||||
LVEF (%), mean ± SD | 51.9 ± 12.8 | 46.5 ± 14.0 | 57.5 ± 8.3 | < 0.001 |
TRV(m/s), median (IQR) | 2.0 (1.8) | 3.8 (0.5) | 1.0 (0) | < 0.001 |
sPAP (mmHg), median (IQR) | 35 (30) | 50 (17.5) | 20 (5) | < 0.001 |
IVS (mm), mean ± SD | 13.9 ± 3.2 | 14.6 ± 3.9 | 13.2 ± 2.1 | 0.011 |
LA (mm) diameter, mean ± SD | 38.2 ± 3.8 | 39.4 ± 3.7 | 36.8 ± 3.4 | < 0.001 |
RA (mm) diameter, mean ± SD | 35.9 ± 4.3 | 38.2 ± 4.5 | 33.6 ± 2.2 | < 0.001 |
Pericardial effusion, n (%) | < 0.001 | |||
No effusion | 61 (43.0) | 13 (18.1) | 48 (68.6) | |
Mild (5–10 mm) | 62 (43.7) | 42 (58.3) | 20 (28.6) | |
Moderate or severe (> 10 mm) | 19 (13.4) | 17 (23.6) | 2 (2.9) | |
Diastolic dysfunction, n (%) | < 0.001 | |||
Normal | 55 (38.5) | 14 (19.2) | 41(58.6) | |
Grade 1 | 55 (38.5) | 33 (45.2) | 22 (31.4) | |
Grade 2 or 3 | 33 (23.1) | 26 (35.6) | 7 (10.0) | |
Laboratory parameters | ||||
Urea (mg/dl), mean ± SD | 149.7 ± 49.0 | 147.1 ± 45.5 | 152.7 ± 53.0 | 0.508 |
NA+ (meq/L), mean ± SD | 134.9 ± 6.3 | 135.2 ± 6.2 | 134.6 ± 6.4 | 0.600 |
K+ (meq/L), mean ± SD | 5.3 ± 0.9 | 5.4 ± 0.9 | 5.3 ± 1.1 | 0.733 |
Glucose (mg/dl), median (IQR) | 115 (56) | 107 (48) | 121 (63) | 0.246 |
Uric acid (mg/dl), mean ± SD | 6.93 ± 1.78 | 6.77 ± 1.70 | 7.12 ± 1.88 | 0.272 |
Creatinine (mg/dl), mean ± SD | 8.9 ± 2.6 | 8.8 ± 2.3 | 9.2 ± 2.8 | 0.316 |
Hemoglobin (g/dl), mean ± SD | 8.4 ± 1.5 | 8.4 ± 1.6 | 8.4 ± 1.4 | 0.958 |
Platelet count (10^3/uL), mean ± SD | 242.0 ± 97.6 | 242.7 ± 102.5 | 241.24 ± 92.6 | 0.932 |
WBC (10^3/uL), mean ± SD | 6.9 ± 2.8 | 6.4 ± 2.6 | 7.5 ± 2.8 | 0.014 |
TSH (uIU/ml), median (IQR) | 3.44 (3.4) | 3.5 (3.5) | 3.2 (3.0) | 0.763 |
Hs-CRP (mg/L), median (IQR) | 11.7 (26.3) | 8.5 (25.7) | 13.6 (28.5) | 0.309 |
ALT (IU/L), median (IQR) | 10 (7) | 10 (9) | 10 (7) | 0.984 |
AST (IU/L), median (IQR) | 15 (8) | 16 (9) | 14 (8) | 0.393 |