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Fig. 3 | The Egyptian Heart Journal

Fig. 3

From: Chronic activation of cardiac Atg-5 and pancreatic Atg-7 by intermittent fasting alleviates acute myocardial infarction in old rats

Fig. 3

Photomicrograph of H&E-stained left ventricle sections of the four studied groups. A Adult group shows average muscle fibers with distinct cell borders (black arrows), and average centrally located nuclei (red arrow) (H&E X 400). B Old group shows most of cardiac muscle fibers with indistinct irregular cell borders and small pyknotic (red arrow) or no nuclei (green arrow), and mildly congested blood vessels (yellow arrow) with mild peri-vascular edema (purple arrow) (H&E X 400). C Old-ISO group shows few scattered cardiac muscle fibers with distinct irregular cell borders (black arrow), bright eosinophilic cytoplasm and small pyknotic (red arrow) or no nuclei (green arrow), and mildly dilated congested blood vessels (yellow arrow) with mild peri-vascular edema (purple arrow) (H&E X 400). D Old-F-ISO group shows viable cardiac muscle fibers with distinct regular cell borders (black arrow), and average nuclei (red arrow), and mildly dilated congested blood vessels (yellow arrow) with mild peri-vascular edema (purple arrow) (H&E X 400). E The histological inflammatory score

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