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Table 4 main predictors of major adverse cardiac events during follow-up identified with univariate analysis

From: Outcomes and prognostic factors of patients treated for in-stent restenosis: a retrospective single-center experience

 

% of MACEs

p value

Clinical characteristics

  

 Hypertension

58% versus 23.2%

0.049

 LDL-cholesterol > 1.4 mmol/l

38.7 versus 18.9%

0.02

 Absence of high-dose statins therapy*

17.9% versus 5.48%

0.03

Angiographic ISR characteristics

  

 Early ISR (< 6 months)

18.1% versus 6.4%

0.042

 ISR of the proximal LAD

14.6% versus 8.9%

0.032

 Diffuse ISR

31% versus 10.3

0.05

 ISR occurring on a BMS

32.7% versus 20.6%

0.03

 Coronary status: triple or double vessel disease

17.8% versus 4.8%

0.016

Technical aspects of the initial angioplasty

  

 Two or more stents per lesion

41.5% versus 19.1%

0.045

 Absence of post-dilatation

25.8% versus 3.4%

0.037

ISR treatment strategy

  

 Medical treatment only

18.8% versus 8.1%

0.046

  1. BMS bare-metal stent, CABG coronary artery bypass graft surgery, DEB drug-eluting balloon, DES drug-eluting stent, ISR in-stent restenosis, LAD left anterior descending artery, MACE major adverse cardiac events, vs versus
  2. *Atorvastatin less than 80 mg once daily or Rosuvastatin less than 20 mg once daily