From: The influence of age and weight on the outcomes of complete atrioventricular septal defect repair
N | Weight 2.4–3.9 kg N = 15 | Weight 4.0–5.9 kg N = 24 | Weight ≥ 6 kg N = 11 | Combined N = 50 | p value | |
---|---|---|---|---|---|---|
Male | 50 | 5 (33%) | 7 (29%) | 5 (45%) | 17 (34%) | 0.639 |
Age (days) | 50 | 125 (92,192) | 184 (152,233) | 416 (260,461) | 191 (148,253) | < 0.001 |
Weight (kg) | 50 | 3.50 (2.95,3.70) | 4.50 (4.20,5.10) | 6.50 (6.30,7.30) | 4.38 (3.80,5.68) | < 0.001 |
Weight (Z score) | 50 | − 5.49 (− 6.09, − 4.17) | − 4.21 (− 4.85, − 3.34) | − 2.80 (− 3.74, − 1.61) | − 4.17 (− 5.04, − 3.23) | < 0.001 |
Down syndrome | 50 | 11 (73%) | 20 (83%) | 10 (91%) | 41 (82%) | 0.501 |
Urgent | 50 | 10 (67%) | 11 (46%) | 3 (27%) | 24 (48%) | 0.133 |
Preop hospital admissions | ||||||
None | 50 | 7 (47%) | 15 (62%) | 4 (36%) | 26 (52%) | 0.050 |
1 | 5 (33%) | 8 (33%) | 3 (27%) | 16 (32%) | ||
2 | 3 (20%) | 0 (0%) | 1 (9%) | 4 (8%) | ||
≥ 3 | 0 (0%) | 1 (4%) | 3 (27%) | 4 (8%) | ||
Preop LOS (days) | 50 | 16.0 (4.0,26.5) | 1.0 (1.0,15.5) | 1.0 (1.0,2.0) | 2.0 (1.0,17.0) | 0.074 |
Total preop ICUS (days) | 50 | 2.0 (0.0,18.5) | 1.0 (0.0,2.2) | 1.0 (0.5,6.5) | 1.0 (0.0,5.8) | 0.405 |
Preop PPV | ||||||
CPAP | 50 | 4 (27%) | 1 (4%) | 0 (0%) | 5 (10%) | 0.017 |
MV | 5 (33%) | 3 (12%) | 1 (9%) | 9 (18%) | ||
None | 6 (40%) | 20 (83%) | 10 (91%) | 36 (72%) | ||
Total preop PPV (days) | 50 | 7.0 (0.0,15.5) | 0.0 (0.0,0.0) | 0.0 (0.0,0.0) | 0.0 (0.0,0.8) | 0.016 |
Preoperative LAVV regurgitation | ||||||
None, trace | 43 | 5 (36%) | 5 (26%) | 4 (40%) | 14 (33%) | 0.827 |
Mild | 5 (36%) | 5 (26%) | 1 (10%) | 11 (26%) | ||
Moderate | 3 (21%) | 7 (37%) | 4 (40%) | 14 (33%) | ||
Severe | 1 (7%) | 2 (11%) | 1 (10%) | 4 (9%) | ||
Preoperative RAVV regurgitation | ||||||
None, trace | 43 | 3 (21%) | 2 (10%) | 3 (30%) | 8 (19) | 0.643 |
Mild | 3 (21%) | 6 (32%) | 2 (20%) | 11 (25%) | ||
Moderate | 6 (43%) | 10 (53%) | 5 (50%) | 21 (49%) | ||
Severe | 2 (14%) | 1 (5%) | 0 (0%) | 3 (7%) | ||
LV hypoplasia | 50 | 0 (0%) | 1 (4%) | 0 (0%) | 1 (2%) | 0.575 |
RV hypoplasia | 50 | 0 (0%) | 0 (0%) | 1 (9%) | 1 (2%) | 0.164 |
Associated COA | 50 | 1 (7%) | 0 (0%) | 0 (0%) | 1 (2%) | 0.304 |
Associated PDA | 50 | 2 (13%) | 5 (21%) | 1 (9%) | 8 (16%) | 0.642 |
Preop furosemide | 50 | 12 (80%) | 21 (88%) | 10 (91%) | 43 (86%) | 0.700 |
Furosemide dose (mg/kg/day) | 50 | 2.76 (1.28,3.13) | 2.56 (1.89,3.00) | 1.67 (1.34,2.39) | 2.42 (1.65,3.00) | 0.431 |
Preop captopril | 50 | 10 (67%) | 18 (75%) | 10 (91%) | 38 (76%) | 0.355 |
Captopril dose (mg/kg/day) | 50 | 1.25 (0.00,1.79) | 1.50 (0.33,2.14) | 1.43 (1.08,2.13) | 1.44 (0.36,2.10) | 0.653 |