Variable | Normal endothelial function n = 14 | Endothelial dysfunction n = 136 | p-value |
---|---|---|---|
Baseline characteristics | |||
Age (years) | 50.86 ± 4.55 | 57.51 ± 5.92 | < 0.001• |
Gender (%) | 0.09* | ||
Males | 5 (35.7%) | 80 (58.8%) | |
Smoking (%) | 2 (14.3%) | 56 (41.2%) | 0.04* |
Hypertension (%) | 5 (35.7%) | 62 (45.6%) | 0.47* |
Diabetes mellitus (%) | 2 (14.3%) | 41 (30.1%) | 0.21* |
Family history (%) | 6 (42.9%) | 27 (19.9%) | 0.04* |
Previous PCI (%) | 1 (7.1%) | 16 (11.8%) | 0.6* |
Previous CABG (%) | 0 (0.0%) | 1 (0.7%) | 0.74* |
Previous myocardial infarction (%) | 0 (0.0%) | 9 (6.6%) | 0.32* |
Previous angina (%) | 3 (21.4%) | 47 (34.6%) | 0.32* |
Myocardial infarction presentation | |||
Territory of infarction (%) | 0.58* | ||
Anterior | 4 (28.6%) | 75 (55.1%) | |
Non-anterior | 10 (71.5%) | 61 (44.8%) | |
Pain to door (hours) | 5.64 ± 2.17 | 5.57 ± 1.92 | 0.89• |
SBP (mmHg) | 117.50 ± 13.97 | 118.20 ± 15.21 | 0.86• |
DBP (mmHg) | 73.57 ± 9.49 | 73.57 ± 12.46 | 0.99• |
Killip class | 0.46* | ||
I | 12 (85.7%) | 105 (77.2%) | |
II | 2 (14.3%) | 31 (22.8%) | |
Angiographic findings | |||
Culprit vessel (%) | 0.3* | ||
LAD | 6 (42.8%) | 85 (62.5%) | |
LCX | 2(14.4%) | 17(12.5%) | |
RCA | 6 (42.8%) | 34 (25%) | |
Thrombus burden grade | 0.36* | ||
I | 7 (50.0%) | 88 (64.7%) | |
II | 7 (50.0%) | 44 (32.4%) | |
III | 0 (0.0%) | 4 (2.9%) | |
Baseline TIMI flow | 0.558* | ||
I | 2 (14.3%) | 14 (10.3%) | |
II | 8 (57.1%) | 63 (46.3%) | |
III | 4 (28.6%) | 59 (43.4%) | |
Post-PCI TIMI flow | 0.37* | ||
I | 0 (0.0%) | 8 (5.9%) | |
II | 1 (7.1%) | 23 (16.9%) | |
III | 13 (92.9%) | 105 (77.2%) | |
Success of epicardial reperfusion by TIMI flow | 0.17* | ||
Non TIMI III | 1 (7.1%) | 31 (22.8%) | |
TIMI III | 13 (92.9%) | 105 (77.2%) | |
Myocardial blush grade | 0.001* | ||
0 | 0 (0.0%) | 21 (15.4%) | |
1 | 1 (7.1%) | 22 (16.2%) | |
2 | 2 (14.3%) | 57 (41.9%) | |
3 | 11 (78.6%) | 36 (26.5%) | |
Success of myocardial reperfusion (by MBG) | 0.06* | ||
MBG 0–1 | 1 (7.1%) | 43 (31.6%) | |
MBG 2–3 | 13 (92.9%) | 93 (68.4%) |