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Table 2 Comparison between endothelial dysfunction and normal endothelial function groups

From: Correlation between endothelial dysfunction and occurrence of no-reflow in patients undergoing post-thrombolysis early invasive percutaneous intervention for ST-elevation myocardial infarction

Variable

Normal endothelial function n = 14

Endothelial dysfunction n = 136

p-value

Baseline characteristics

Age (years)

50.86 ± 4.55

57.51 ± 5.92

< 0.001•

Gender (%)

  

0.09*

  Males

5 (35.7%)

80 (58.8%)

Smoking (%)

2 (14.3%)

56 (41.2%)

0.04*

Hypertension (%)

5 (35.7%)

62 (45.6%)

0.47*

Diabetes mellitus (%)

2 (14.3%)

41 (30.1%)

0.21*

Family history (%)

6 (42.9%)

27 (19.9%)

0.04*

Previous PCI (%)

1 (7.1%)

16 (11.8%)

0.6*

Previous CABG (%)

0 (0.0%)

1 (0.7%)

0.74*

Previous myocardial infarction (%)

0 (0.0%)

9 (6.6%)

0.32*

Previous angina (%)

3 (21.4%)

47 (34.6%)

0.32*

Myocardial infarction presentation

Territory of infarction (%)

  

0.58*

  Anterior

4 (28.6%)

75 (55.1%)

  Non-anterior

10 (71.5%)

61 (44.8%)

Pain to door (hours)

5.64 ± 2.17

5.57 ± 1.92

0.89•

SBP (mmHg)

117.50 ± 13.97

118.20 ± 15.21

0.86•

DBP (mmHg)

73.57 ± 9.49

73.57 ± 12.46

0.99•

Killip class

  

0.46*

  I

12 (85.7%)

105 (77.2%)

  II

2 (14.3%)

31 (22.8%)

Angiographic findings

Culprit vessel (%)

  

0.3*

  LAD

6 (42.8%)

85 (62.5%)

  LCX

2(14.4%)

17(12.5%)

  RCA

6 (42.8%)

34 (25%)

Thrombus burden grade

  

0.36*

  I

7 (50.0%)

88 (64.7%)

  II

7 (50.0%)

44 (32.4%)

  III

0 (0.0%)

4 (2.9%)

Baseline TIMI flow

  

0.558*

  I

2 (14.3%)

14 (10.3%)

  II

8 (57.1%)

63 (46.3%)

  III

4 (28.6%)

59 (43.4%)

Post-PCI TIMI flow

  

0.37*

  I

0 (0.0%)

8 (5.9%)

  II

1 (7.1%)

23 (16.9%)

  III

13 (92.9%)

105 (77.2%)

Success of epicardial reperfusion by TIMI flow

  

0.17*

  Non TIMI III

1 (7.1%)

31 (22.8%)

  TIMI III

13 (92.9%)

105 (77.2%)

Myocardial blush grade

  

0.001*

  0

0 (0.0%)

21 (15.4%)

  1

1 (7.1%)

22 (16.2%)

  2

2 (14.3%)

57 (41.9%)

  3

11 (78.6%)

36 (26.5%)

Success of myocardial reperfusion (by MBG)

  

0.06*

  MBG 0–1

1 (7.1%)

43 (31.6%)

  MBG 2–3

13 (92.9%)

93 (68.4%)

  1. CABG Coronary artery bypass graft, DBP Diastolic blood pressure, LAD Left anterior descending artery, LCX Left circumflex artery, MBG Myocardial blush grade, PCI Percutaneous intervention, RCA Right coronary artery, SBP Systolic blood pressure, TIMI Thrombolysis in myocardial infarction
  2. *: Chi-square test; •: Independent t-test