30-d mortality | P value | ||
---|---|---|---|
Yes (n = 60) | No (n = 188) | ||
Baseline demographics & clinical criteria | |||
Age (years) | 56 ± 10 | 47 ± 13 | < 0.001* |
Gender | |||
Males | 29 (48.3) | 99 (52.7) | 0.559 |
Females | 31 (51.7) | 89 (47.3) | |
Mean arterial pressure (mmHg) | 52 ± 10 | 70 ± 11 | < 0.001* |
Temperature (°) | 37.9 ± 0.5 | 38 ± 0.3 | 0.073 |
PH | 7.2 ± 0.07 | 7.37 ± 0.08 | < 0.001* |
Heart rate (bpm) | 103 ± 7 | 102 ± 5 | 0.469 |
Respiratory rate (cycles/min) | 19 ± 3 | 20 ± 3 | 0.686 |
Sodium (meq/L) | 131 ± 5 | 137 ± 3 | < 0.001* |
Potassium (meq/L) | 3.9 ± 1 | 4 ± 0.6 | 0.336 |
Creatinine (mg/dl) | 2.9 (0.8–5.2) | 1.05 (0.6–5.5) | < 0.001* |
Acute renal failure | 56 (93.3) | 53 (28.2) | < 0.001* |
Hematocrit (%) | 29 ± 4 | 35 ± 4 | < 0.001* |
WBC count | 23.2 ± 5.5 | 18.8 ± 3 | < 0.001* |
Glasgow Coma Scale | 9 (3–15) | 15 (5–15) | < 0.001* |
FiO2 | |||
> 50% | 39 (65) | 59 (31.4) | < 0.001* |
< 50% | 21 (35) | 129 (68.6) | |
APACHE 2 score | 31 (12–41) | 6 (1–25) | < 0.001* |
Fluid received 6 h before echo (ml) | 1500 (500–3500) | 1500 (500–3000) | 0.438 |
Receipt of vasopressors during echo | 56 (93.3) | 32 (17) | < 0.001* |
Norepinephrine equivalent dose (ug/kg/min) | 1.2 (0.5–2.1) | 0.7 (0.2–1.5) | < 0.001* |
Ventilated during echo | 29 (48.3) | 4 (2.1) | < 0.001* |
PaO2/FiO2 ratio | 289 ± 46 | 335 ± 27 | < 0.001* |
Ventilator-free days (days) | 0 (0 – 8) | 30 (24–30) | < 0.001* |
Baseline echocardiographic criteria | |||
TAPSE (cm) | 17 ± 3.7 | 19.5 ± 4.1 | < 0.001* |
RV end-systolic area (cm2) | 15.83 ± 4.97 | 14.13 ± 3.23 | 0.015* |
RV end-diastolic area (cm2) | 21.87 ± 4.53 | 21.24 ± 3.94 | 0.332 |
RV fractional area change (%) | 30.91 ± 8.38 | 34.96 ± 8.51 | 0.001* |
LVEF (%) | 58.1 ± 13.6 | 64.8 ± 7.8 | < 0.001* |
LV global longitudinal strain (GLS) (%) | − 18.9 ± 4.5 | − 19.5 ± 3.3 | 0.365 |
LV E/E' | 9.39 ± 4.19 | 7.82 ± 3.03 | 0.009* |