All rheumatic diseases | SLE (n = 30) | Systemic sclerosis (n = 21) | Rheumatoid arthritis (n = 10) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
HC (n = 64) | Cases (n = 64) | P value | HC | SLE | p value | HC | SSc | p value | HC | RA | p value | |
LVEF (%) | 55.16 ± 0.88 | 53.91 ± 6.00 | 0.104 | 55.17 ± 0.91 | 54.33 ± 2.54 | 0.099 | 55.24 ± 1.09 | 55.00 ± 2.24 | 0.663 | 55.00 ± 0.00 | 54.50 ± 1.58 | 0.331 |
LVEDD (mm) | 40.03 ± 3.35 | 47.23 ± 3.82 | < 0.001 | 39.57 ± 3.45 | 47.03 ± 4.13 | < 0.001 | 39.48 ± 2.66 | 46.95 ± 3.58 | < 0.001 | 41.90 ± 3.76 | 48.20 ± 3.05 | 0.001 |
LVESD (mm) | 23.27 ± 4.84 | 30.86 ± 4.90 | < 0.001 | 23.10 ± 4.55 | 30.37 ± 5.23 | < 0.001 | 22.19 ± 4.66 | 29.52 ± 3.43 | < 0.001 | 25.30 ± 5.62 | 33.50 ± 3.92 | 0.001 |
RVEDD (mm) | 28.05 ± 1.69 | 28.66 ± 2.69 | 0.128 | 27.90 ± 1.71 | 28.37 ± 3.00 | 0.463 | 28.00 ± 1.55 | 28.38 ± 2.08 | 0.505 | 28.30 ± 2.06 | 29.00 ± 1.83 | 0.431 |
RA area (cm2) | 11.41 ± 1.90 | 13.07 ± 2.85 | < 0.001 | 11.50 ± 1.80 | 13.17 ± 3.42 | 0.022 | 11.62 ± 2.29 | 12.67 ± 2.35 | 0.152 | 11.10 ± 1.45 | 13.05 ± 2.17 | 0.029 |
RV septal strain (%) | 21.05 ± 2.11 | 16.33 ± 4.00 | < 0.001 | 20.83 ± 2.35 | 16.03 ± 4.31 | < 0.001 | 20.67 ± 1.93 | 15.90 ± 2.93 | < 0.001 | 22.00 ± 1.49 | 17.40 ± 4.95 | 0.017 |
RV free wall strain (%) | 26.47 ± 2.59 | 23.23 ± 4.14 | < 0.001 | 26.73 ± 1.87 | 23.07 ± 4.00 | < 0.001 | 26.19 ± 1.89 | 22.57 ± 3.70 | < 0.001 | 25.80 ± 4.76 | 24.30 ± 4.52 | 0.479 |
Average longitudinal RV strain (%) | 24.09 ± 2.08 | 19.31 ± 3.68 | < 0.001 | 24.10 ± 1.99 | 19.03 ± 3.52 | < 0.001 | 23.48 ± 1.89 | 18.67 ± 3.10 | < 0.001 | 24.80 ± 2.25 | 20.70 ± 4.57 | 0.020 |
TAPSE (mm) | 25.61 ± 1.53 | 21.70 ± 2.99 | < 0.001 | 25.77 ± 1.28 | 21.77 ± 2.49 | < 0.001 | 25.62 ± 1.53 | 22.33 ± 2.94 | < 0.001 | 25.10 ± 2.28 | 20.90 ± 3.32 | 0.004 |
RV systolic myocardial velocity (cm/s) | 15.86 ± 1.48 | 12.73 ± 2.30 | < 0.001 | 15.97 ± 1.40 | 12.70 ± 2.31 | < 0.001 | 16.00 ± 1.34 | 13.05 ± 2.06 | < 0.001 | 15.10 ± 2.02 | 12.50 ± 1.51 | 0.004 |
RV fractional area change (%) | 37.83 ± 3.13 | 29.53 ± 7.18 | < 0.001 | 37.67 ± 2.93 | 29.44 ± 7.37 | < 0.001 | 37.14 ± 3.18 | 27.42 ± 6.41 | < 0.001 | 38.80 ± 3.22 | 32.30 ± 4.42 | 0.001 |
IVC diameter (mm) | 12.06 ± 2.14 | 15.03 ± 3.18 | < 0.001 | 11.67 ± 2.12 | 15.07 ± 2.91 | < 0.001 | 12.48 ± 2.46 | 15.52 ± 3.38 | 0.002 | 12.00 ± 1.33 | 13.30 ± 2.11 | 0.120 |
SPAP | 19.19 ± 1.92 | 30.61 ± 8.51 | < 0.001 | 19.17 ± 1.58 | 30.43 ± 9.84 | < 0.001 | 18.90 ± 2.00 | 31.81 ± 7.42 | < 0.001 | 20.20 ± 2.62 | 27.80 ± 5.10 | 0.001 |