Table 1 The Dutch Lipid Clinic Network criteria

Family history

(A) First-degree relative known with premature CAD and/or a first-degree relative with LDL-C > 95th centile

1

(B) First-degree relative with tendon xanthoma and/or children < 18 with LDL-C > 95th centile

2

Clinical history

(A) Patient has premature CAD

2

(B) Patient has premature cerebral/peripheral vascular disease

1

Physical examination

Presence of

Tendon xanthoma

6

Arcus cornealis below the age of 45 years

4

LDL-C

(A) > 8.5 mmol/L (more than ~ 330 mg/dl)

8

(B) 6.5–8.4 mmol/L (~ 250–329 mg/dl)

5

(C) 5.0–6.4 mmol/L (~ 190–249 mg/dl)

3

(D) 4.0–4.9 mmol/L(~ 155–189 mg/dl)

1

Definite FH

Score > 8

Probable FH

Score 6–8

Possible FH

Score 3–5

No diagnosis

Score < 3