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Table 1 Demographic, clinical characteristics, laboratory, and Echocardiographic parameters of the study groups

From: Relation between aortic elasticity parameters and SYNTAX score in postmenopausal diabetic women

  

Low SS (n = 61)

Intermediate SS (n = 70)

High SS (n = 69)

F/ X2

P. value

P1

P2

P3

Age

Mean ± SD

54.21 ± 5.00

56.37 ± 5.78

60.38 ± 5.59

21.351

0.001*

0.026*

0.001*

0.001*

Smoking

N

2

1

2

0.526

0.769

0.480

0.900

0.551

 

%

3.3%

1.4%

2.9%

     

Hypertension

N

19

21

19

0.216

0.898

0.887

0.651

0.748

 

%

31.1%

30.0%

27.5%

     

BMI (Kg/m2)

Mean ± SD

30.33 ± 3.65

29.52 ± 3.97

30.06 ± 3.45

0.831

0.437

0.211

0.677

0.389

Medications

         

ACEI

N

36

44

39

0.587

0.746

0.653

0.774

0.446

 

%

60%

63%

56%

     

BB

N

26

31

33

0.381

0.828

0.848

0.552

0.675

 

%

42%

44%

48%

     

CCB

N

10

14

13

0.287

0.865

0.595

0.715

0.863

 

%

16%

20%

19%

     

Statins

N

36

43

40

0.182

0.914

0.778

0.904

0.678

 

%

59%

61%

58%

     

Anti-diabetic treatment

         

Insulin

N

20

21

25

0.612

0.736

0.732

0.680

0.435

 

%

32%

30%

36%

     

Oral hypoglycaemics

N

35

41

39

0.063

0.970

0.890

0.922

0.807

 

%

57%

58%

56%

     

Insulin + oral hypoglycaemics

N

6

8

5

0.719

0.698

0.769

0.596

0.397

 

%

10%

11%

7%

     

Time since diabetes diagnosis (Years)

Mean ± SD

5.54 ± 2.64

5.50 ± 2.63

5.68 ± 2.70

0.088

0.916

0.930

0.764

0.688

Age at menopause (Year)

Mean ± SD

47.62 ± 1.53

47.86 ± 1.52

47.90 ± 1.43

0.633

0.532

0.371

0.294

0.870

HBA1c (%)

Mean ± SD

7.02 ± 0.62

7.01 ± 0.62

7.01 ± 0.55

0.002

0.998

0.971

0.951

0.979

LDL (mg/dl)

Mean ± SD

130.36 ± 42.28

137.62 ± 37.63

127.90 ± 38.21

1.143

0.321

0.293

0.722

0.147

HDL (mg/dl)

Mean ± SD

44.56 ± 8.05

45.51 ± 7.40

44.23 ± 7.73

0.516

0.597

0.480

0.811

0.328

TG (mg/dl)

Mean ± SD

208.75 ± 47.15

214.07 ± 44.16

206.39 ± 44.79

0.523

0.594

0.504

0.767

0.319

LVEF %

Mean ± SD

60.79 ± 5.00

60.71 ± 5.12

60.90 ± 4.92

0.024

0.977

0.934

0.899

0.829

Heart Rate (B/min)

Mean ± SD

66.95 ± 6.62

65.87 ± 6.32

66.09 ± 6.37

0.504

0.605

0.339

0.445

0.844

SBP (mmHg)

Mean ± SD

113.52 ± 12.92

105.36 ± 8.40

106.01 ± 10.38

11.625

0.001*

0.001*

0.001*

0.716

DBP (mmHg)

Mean ± SD

83.11 ± 9.92

74.71 ± 7.01

72.46 ± 8.34

28.190

0.001*

0.001*

0.001*

0.118

Pulse pressure

Mean ± SD

30.41 ± 6.08

30.64 ± 5.24

33.55 ± 5.82

6.340

0.002*

0.816

0.002*

0.003*

AoS(cm)

Mean ± SD

3.40 ± 0.49

3.38 ± 0.49

3.40 ± 0.48

0.080

0.923

0.733

0.995

0.730

AoD (cm)

Mean ± SD

3.19 ± 0.51

3.18 ± 0.51

3.30 ± 0.48

1.191

0.306

0.868

0.228

0.156

Aortic distensibility(cm2/dyn/103)

Mean ± SD

4.83 ± 2.19

4.32 ± 1.84

2.01 ± 0.67

53.748

0.001*

0.079

0.001*

0.001*

Aortic strain %

Mean ± SD

6.99 ± 2.86

6.51 ± 2.73

3.27 ± 0.86

51.279

0.001*

0.239

0.001*

0.001*

Aortic stiffness index

Mean ± SD

2.449 ± 0.470

2.482 ± 0.463

3.062 ± 0.230

50.036

0.001*

0.641

0.001*

0.001*

SV (ml)

Mean ± SD

68.85 ± 8.91

69.27 ± 7.80

68.59 ± 8.16

0.118

0.888

0.773

0.859

0.630

SVi (ml/m2)

Mean ± SD

44.06 ± 7.46

43.74 ± 4.19

43.78 ± 3.75

0.069

0.933

0.731

0.764

0.965

PP/SVi

Mean ± SD

0.81 ± 0.97

0.71 ± 0.16

0.77 ± 0.14

0.601

0.549

0.279

0.652

0.514

  1. P1, significance between Low & Intermediate SS; P2, significance between Low & High SS; P3, significance between Intermediate & High SS; SS, YNTAX score; HBA1c, Haemoglobin A1c; LDL, Low-Density Lipoprotein; HDL, Low-Density Lipoprotein; TG, Triglycerides BMI, Body Mass Index; ACEI, Angiotensin-converting enzyme inhibitors; BB, Beta-blockers; CCB, Calcium channel blockers; B/min (beat/ minute); LVEF, Left Ventricular Ejection Fraction; SBP, Systolic Blood Pressure; DBP, Diastolic Blood Pressure; AO, Aorta;SV, Stroke Volume; SVI, Stroke Volume Index; PP, Pulse pressure
  2. *Significant P-value