Articles

Implementation of clinical audit to improve adherence to guideline-recommended therapy in acute coronary syndrome

Despite global consensus on the management of acute coronary syndrome (ACS), implementation of strategies to improve adherence of guideline-directed medical therapy (GDMT) remains sub-optimal, especially in de...

Authors: Nimmy Elizabeth George, Aashiq Ahamed Shukkoor, Noel Joseph, Ramasamy Palanimuthu, Tamilarasu Kaliappan and Rajendiran Gopalan

Investigation of the correlation between cardiac parameters and aortic diameter in patients with ascending aortic aneurysm

Aortic aneurysms (AA) are enlargement of the aorta silently until diagnosing, not detectable on physical examination, and usually incidentally discovered during radiologic scanning for other reasons. It can ge...

Authors: Mustafa Etli, Seda Avnioglu, Halil Yilmaz and Oguz Karahan

The central arterial stiffness parameters in decompensated versus compensated states of heart failure: a paired comparative cohort study

Arterial stiffness is strongly linked to the pathogenesis of heart failure and the development of acute decompensation in patients with stable chronic heart failure. This study aimed to compare arterial stiffn...

Authors: Ahmed El Fol, Waleed Ammar, Yasser Sharaf and Ghada Youssef

Prevalence of obesity and its association with cardiometabolic risk factors, heart failure phenotype and mortality among patients hospitalized for heart failure in Egypt

Obesity is an established risk factor for cardiometabolic disease and heart failure (HF). Nevertheless, the relationship between obesity and HF mortality remains controversial.

Authors: Ahmed Hassanin, Mahmoud Hassanein, Gregg M. Lanier, Mohamed Sadaka, Mohamed Rifaat and Mohamed Sanhoury

Bilirubin levels as an independent predictor of myocarditis in patients with COVID-19

Myocardial damage worsens the clinical course and prognosis of coronavirus disease 2019 (COVID-19) patients. High total bilirubin levels have been associated with a poor prognosis in COVID-19. This study aimed...

Authors: Muharrem Said Cosgun

Egyptian practical guidance in hypertriglyceridemia management 2021

Hypertriglyceridemia (HTG) is a very common, yet underappreciated problem in clinical practice. Elevated triglyceride (TG) levels are independently associated with atherosclerotic cardiovascular disease (ASCVD...

Authors: Hesham Salah El Din Taha, Hossam Kandil, Nabil Farag, Abbas Oraby, Magdy El Sharkawy, Fouad Fawzy, Hossam Mahrous, Juliette Bahgat, Mina Samy, Mohamed Aboul, Mostafa Abdrabou and Mirna Mamdouh Shaker

Kounis syndrome secondary to nimesulide ingestion: a case report

Kounis syndrome, also known as "allergic myocardial infarction," is a rare co-occurrence of acute coronary syndrome (ACS) in the setting of hypersensitivity reaction to any agent. Non-steroidal anti-inflammato...

Authors: Yamasandi Siddegowda Shrimanth, Krishna Santosh Vemuri, Atit A. Gawalkar, Soumitra Ghosh, Jyothi Vijay, Thammannagowda Prarthana and Bhupendra Kumar Sihag

Cardiac hydatid cyst presenting as ventricular arrhythmia: a case report

Hydatid disease caused by Echinococcus granulosus commonly involves the liver followed by lungs. Cardiac involvement is a rare occurrence and presents a challenging scenario.

Authors: Abdullah Ameen, Kiran Hilal, Asra Shaikh, Faheemullah Khan and Saulat Fatimi

C₂HEST score for atrial fibrillation risk prediction models: a Diagnostic Accuracy Tests meta-analysis

This meta-analysis aimed to assess the value of the C₂HEST score to facilitate population screening and detection of AF risk in millions of populations and validate risk scores and their composition and discrimin...

Authors: Habib Haybar, Kimia Shirbandi and Fakher Rahim

Risk of drug-induced cardiac arrhythmia during COVID-19 therapeutic treatment

Therapeutic treatment of severe COVID-19 infection involves the administration of multiple pharmacologic agents to reduce the risk of serious complications; this may result in drug interactions and possible ad...

Authors: Antonio Vitiello and Francesco Ferrara

The role of far-field intravascular ultrasound in transcatheter aortic valve replacement

Precise and accurate characterization of the aortic valve complex is a vital step in the procedure planning for transcatheter aortic valve replacement (TAVR). Far-field intravascular ultrasound (IVUS) is a nov...

Authors: Ahmed Hassanin, Hasan Ahmad, Massoud Leesar and Diaa Hakim

Simultaneous radio-ulnar cannulation: shifting gears from ‘feasibility’ to ‘applicability’

Conventionally, routes of vascular access commonly include femoral and radial arteries with brachial, ulnar and subclavian arteries being rarely used for coronary interventions. Non-femoral arterial access is ...

Authors: Ankit Kumar Sahu, Sudesh Prajapati and Danish Hasan Kazmi

Decellularized versus cryopreserved pulmonary allografts for right ventricular outflow tract reconstruction during the Ross procedure: a meta-analysis of short- and long-term outcomes

The ideal conduit for repair of the right ventricular outflow tract (RVOT) during the Ross procedure remains unclear and has yet to be fully elucidated. We perform a pairwise meta-analysis to compare the short...

Authors: Adham Ahmed, Sarah Ahmed, Kathryn S. Varghese, Dave M. Mathew, Roshan Pandey, Dillon O. Rogando, Stephanie A. Salazar, Peter J. Fusco and Kenneth H. Levy

Mortality probabilities after revascularization and medical therapy in CAD patients under 60 years old: a meta-analysis study

To estimate death probabilities after coronary artery bypass graft (CABG), percutaneous coronary intervention (PCI), and medical therapy (MT) in patients under 60 years old. We conducted a search systematic on...

Authors: Mohammad Afrouzi, Farbod Ebadi Fard Azar, Ali Aboutorabi, Marjan Hajahmadi and Seyed Javad Ebadi

The effect of virtual reality distraction on reducing patients' anxiety before coronary angiography: a randomized clinical trial study

Coronary angiography is used as a qualified method to diagnose coronary heart disease. However, patients undergoing coronary angiography experience a great deal of anxiety. The present study is aimed at invest...

Authors: Mostafa Keshvari, Mohammad Reza Yeganeh, Ezzat Paryad, Zahra Atrkar Roushan and Moluk Pouralizadeh

Prevalence and predictors of heart failure among patients on maintenance hemodialysis therapy at Muhimbili National Hospital in Tanzania: a cross-sectional study

Heart failure among patients on hemodialysis therapy portends poor outcomes. Traditional risk factors like aging, hypertension and diabetes mellitus are relatively common in these patients and may not accurate...

Authors: Puneet Kishore Bramania, Paschal Joseph Ruggajo and Francis Fredrick Furia

The associations between coronary artery disease, and non-alcoholic fatty liver disease by computed tomography

Non-alcoholic fatty liver disease (NAFLD) is increasing in recognition as a hepatic condition that is unrelated to significant alcoholic consumption, but has rather, been suggested to constitute cardiovascular...

Authors: Samira Saraya, Mahmoud Saraya, Mohamed Mahmoud, Mohamed Galal, Hazem Hamed Soliman and Mariam Raafat

Time to think beyond door to balloon time: significance of total ischemic time in STEMI

Significance of total ischemic time (TIT) in the context of ST-segment elevation myocardial infarction (STEMI) is still controversial. Therefore, in this study, we have evaluate the association of TIT with imm...

Authors: Sanam Khowaja, Salik Ahmed, Rajesh Kumar, Jehangir Ali Shah, Kamran Ahmed Khan, Naveed Ullah Khan, Tahir Saghir, Syed Nadeem Hasan Rizvi, Nadeem Qamar and Musa Karim

Cardiovascular disease risk factors among undergraduate medical students in a tertiary care centre of eastern India: a pilot study

Handful studies report the prevalence of cardiovascular disease (CVD) risk factors among medical students from India and none from the eastern part of the country.

Authors: Somnath Mukhopadhay, Anindya Mukherjee, Dibbendhu Khanra, Biaus Samanta, Avik Karak and Santanu Guha

SGLT2 inhibitors in heart failure with reduced ejection fraction

Sodium – glucose co-transporter 2 (SGLT2) inhibitors reduce blood glucose by inhibiting reabsorption of glucose from the proximal renal tubules. Initial studies showed that apart from reducing blood glucose th...

Authors: Uday Sankar Das, Aritra Paul and Suvro Banerjee

Predictors of aortic clamp time duration and intensive care unit length of stay in elective adult cardiac surgery

Aortic cross-clamp utilized during cardiac surgery facilitates motionless and bloodless surgical field. However, the duration of clamp time has an inverse effect on early post-operative recovery period. In thi...

Authors: Ashraf Fadel Moh’d, Hayel Talal Al-Odwan, Salah Altarabsheh, Zeid Mohammad Makahleh and Mohammad Abdallah Khasawneh

Global longitudinal strain detects subtle left ventricular systolic dysfunction in Duchenne muscular dystrophy patients and carriers

With the continuous improvement of the respiratory care of Duchenne muscular dystrophy patients, cardiac manifestations (heart failure and arrhythmias) become the leading causes of morbidity and mortality. Ear...

Authors: Mahmoud Shehta, Mona Mostafa Rayan, Nagia Aly Fahmy, Ahmed Onsy and Islam Bastawy

Multidetector computed tomography for patients with congenital heart disease: a multi-center registry from Africa and Middle East; patients’ characteristics and procedural safety

We aimed to establish a clinical registry for patients with congenital heart disease who referred to multidetector computed tomography in our country, to describe the pattern and clinical profile of such patie...

Authors: Dina Adel Ezzeldin, Mohamed Saber Hafez and Amr Mansour

Multidetector computed tomography study to measure thoracic aorta diameters in Egyptian population

The aorta is the largest and strongest artery in the body that plays an important role in the control of systemic vascular resistance and heart rate. Aortic diseases contribute to the wide spectrum of arterial...

Authors: Ahmed Shehata Mohamed Ismail, Shareefa Ali Mohammad Al-Suraimi, Hossam El Din Ghanem El Hossary, Mohamed Ali Salem and Hossam Ibrahim Hamed Kandil

The association between 24-h blood pressure variability and major adverse cardiac events (MACE) in hospitalized patients with acute myocardial infarction: a retrospective cohort study

Acute myocardial infarction (AMI) is major cardiovascular disease that causes high morbidity and mortality. In AMI, ischemia and necrosis affected some cardiomyocytes leading to a decrease in myocardial contra...

Authors: Harefa, Ika Prasetya Wijaya, Muhadi, Cleopas Martin Rumende, Sally Aman Nasution, Sukamto Koesnoe, Maruhum Bonar Marbun and Hamzah Shatri

Knowledge, attitudes and practices survey of cardiac rehabilitation among cardiologists and cardiac surgeons in Lebanon

Cardiovascular diseases (CVDs) are among the leading causes of morbidity and mortality worldwide. Over three quarters of the cardiovascular deaths take place in low and middle-income countries. Despite the ben...

Authors: Rebecca Farah, Wim Groot and Milena Pavlova

Impact of percutaneous ventricular septal defect closure on left ventricular remodeling and function

Ventricular septal defect (VSD) is the most common congenital heart disease. In patients with large VSD, left side chambers are subjected to volume overload with subsequent chambers dilatation and eccentric le...

Authors: Amr Abdel Aal, Housam M. Hassan, Dina Ezzeldin and Maiy El Sayed

Iron replacement therapy in heart failure: a literature review

Heart failure (HF) is a major global challenge, emphasised by its designation as the leading cause of hospitalisation in those aged 65 and above. Approximately half of all patients with HF have concurrent iron...

Authors: Hassan Ismahel and Nadeen Ismahel

Efficacy and safety of hydro-mechanical defragmentation in intermediate- and high-risk pulmonary embolism

Pulmonary embolism (PE) is the third most common acute cardiovascular syndrome. Percutaneous catheter directed hydro-mechanical defragmentation (HMD) is one of the recommended treatment options for PE in patie...

Authors: Ayman K. M. Hassan, Heba Ahmed, Yousef Ahmed, Abd-Elazim Abo Elfadl and Amany Omar

Outcome of ductus arteriosus stenting including vertical tubular and convoluted tortuous ducts with emphasis on technical considerations

Ductal stenting is the preferred method of securing adequate pulmonary blood flow in patients with duct-dependent pulmonary circulation. The main limitation in most centers is the difficult vertical tubular or...

Authors: Saud Bahaidarah, Jameel Al-Ata, Naif Alkhushi, Ahmad Azhar, Zaher Zaher, Bayan Alnahdi, Mohamed Abdelsalam, Ahmed Elakaby, Ahmed Dohain and Gaser Abdelmohsen

Inhaled prostacyclin analogues in COVID-19 associated acute respiratory distress syndrome: scientific rationale

COVID-19 associated acute respiratory distress syndrome (CARDS) is a severe form of SARS CoV-2 infection and affects about 15–30% of hospitalized patients with a high mortality rate. Growing research and data ...

Authors: Eka Prasetya Budi Mulia and Kevin Luke

Association of COVID-19 infection with large thrombi in left and right atrial appendages

Multiple intra-atrial thrombi are found rarely except in the presence of prosthetic valves, intra-cardiac devices, structural connections like foramen ovale and thrombophilia.

Authors: Saeed Ghodsi, Sara Taghi, Zahra Alizadeh-Sani, Yaser Jenab, Zahra Hosseini and Laura Vaskelyte

Giant descending aortic pseudo-aneurysm in an adult man with uncorrected aortic coarctation

Aortic coarctation (CoAo) accounts for 6 to 8% of all congenital heart diseases and occurs two to five times more often in males. The uncorrected aortic coarctation is complicated by hypertension, ascending an...

Authors: Zahra Jabbary and Mehrnoush Toufan

Pre-procedural predictors for multiple clips in percutaneous edge-to-edge mitral valve repair

Percutaneous mitral valve (MV) clipping for mitral regurgitation (MR) revolutionized MV repair; however, valve anatomies and pathologies vary. Often multiple clips are required, and predicting this pre-procedu...

Authors: Mohammad El Garhy, Bernward Lauer, Björn Göbel, Lisa C. Costello-Boerrigter, Carsten Salomon, Harald Lapp and Marc-Alexander Ohlow

Stenting deferral in primary percutaneous coronary intervention: exploring benefits and suitable interval in heavy thrombus burden

Deferred stenting, despite being successful in early studies, showed no benefit in recent trials. However, these trials were testing routine deferral; not in patients with heavy thrombus burden.

Authors: Ahmed M. Magdy, Salwa R. Demitry, Hosam Hasan-Ali, Mohamed Zaky, Mohamed Abd El-Hady and Mohamed Abdel Ghany

Cardiovascular system and coronavirus disease-2019 (COVID-19): mutual injuries and unexpected outcomes

Cardiovascular system involvement in coronavirus disease-2019 (COVID-19) has gained great interest in the scientific community.

Authors: Eman Sobh, Muhammad Saad Reihan, Tamer M. S. Hifnawy, Khloud Gamal Abdelsalam, Sohaila Sabry Awad, Nehal Mostafa Hamed Mahmoud, Nariman A. Sindi and Hani A. Alhadrami

Contemporary approach to understand and manage COVID-19-related arrhythmia

Arrhythmia, one of the most common complications of COVID-19, was reported in nearly one-third of diagnosed COVID-19 patients, with higher prevalence rate among ICU admitted patients. The underlying etiology f...

Authors: Omnia Azmy Nabeh, Maiada Mohamed Helaly, Rahma Menshawey, Esraa Menshawey, Mohammed Mansoor Matooq Nasser and Ahmed Mohamed Diaa El-deen

Anemia in heart failure: still an unsolved enigma

Anemia affects one-third of heart failure patients and is associated with increased morbidity and mortality. Despite being one of the commonest comorbidities associated with heart failure, there is a significa...

Authors: Yash Paul Sharma, Navjyot Kaur, Ganesh Kasinadhuni, Akash Batta, Pulkit Chhabra, Samman Verma and Prashant Panda

Aortic remodelling and false lumen changes after the frozen elephant trunk technique using the thoraflex hybrid stented graft for aortic dissection

Despite the marked improvement in the aortic dissection repair techniques, residual dissected aorta with a patent false lumen remains an issue. So, the aim of our study is to observe the effect of inserting th...

Authors: Mostafa Mehanna, Moustafa Elhamami, Ahmed Abolkasem, Bassem Ramadan, Abdallah Almaghraby and Jorge Mascaro

Complex and multilevel left ventricular outflow tract obstruction: What can 3D echocardiography add?

Subaortic obstruction by a membrane or systolic anterior motion of the mitral valve leaflets is usually suspected in young patients, especially if the anatomy of the aortic valve is not clearly stenotic and un...

Authors: Hoda Abdelgawad, Mahmoud Shehata, Mahmoud Abdelnabi, Abdallah Almaghraby and Mohamed Ayman Abdel-Hay

The role of NKX2-5 gene polymorphisms in congenital heart disease (CHD): a systematic review and meta-analysis

The gene NKX2-5 is a key transcription factor that plays an essential role in normal cardiac development. Although some recent studies have studied the role of polymorphisms in the NKX2-5 gene in congenital heart...

Authors: Sana Ashiq, Kanwal Ashiq and Muhammad Farooq Sabar

Clinical utility of fetal echocardiography: an Egyptian center experience

The impact of early diagnosis of fetal cardiac abnormalities on the postnatal outcome has been controversial in literature. We aimed to evaluate the role of fetal echocardiography (FE) as a diagnostic tool for...

Authors: Marwa Moustapha Al-Fahham, Nada Ayman Gad, Ahmed Ramy Mohamed Ramy and Nevin Mamdouh Habeeb

Direct comparison of non-vitamin K antagonist oral anticoagulant versus warfarin for stroke prevention in non-valvular atrial fibrillation: a systematic review and meta-analysis of real-world evidences

To overcome the several drawbacks of warfarin, non-vitamin K antagonist oral anticoagulants (NOACs) were developed. Even though randomized controlled trials (RCTs) provided high-quality evidence, the real-worl...

Authors: Yoga Waranugraha, Ardian Rizal, Mokhamad Fahmi Rizki Syaban, Icha Farihah Deniyati Faratisha, Nabila Erina Erwan and Khadijah Cahya Yunita

Acute pulmonary embolism in a patient with hepatitis C virus infection and hepatocellular carcinoma: a case report

Cardiac metastases in hepatocellular carcinoma patients are infrequently encountered and usually associated with a very poor prognosis.

Authors: Mahmoud Abdelnabi, Yehia Saleh, Abdallah Almaghraby, Özge Özden Tok, Hoda Abdelgawad and Sherif Abd ElSamad

Is coronary artery tortuosity a precursor of atherosclerosis and/or left ventricular diastolic dysfunction?

Authors: Zainab Atiyah Dakhil

Early results from an Egyptian transcatheter aortic valve registry (Egy-TVR)

Transcatheter aortic valve implantation (TAVI) is a well-established and standard therapy for patients with symptomatic severe aortic stenosis at moderate or high risk for surgical aortic valve replacement. Re...

Authors: Hesham Bahaa, Yasser Sadek, Ahmad E. Mostafa, Diaa Kamal, Mahmoud Baraka, Mohammad Abdelghani, Ahmed Hassan, Ahmed Shehata, Magdy Abdelhamid and Ahmed Elguindy

Cor triatriatum with supramitral ring: “cor tetratriatum”, associated with Raghib syndrome with Eisenmenger syndrome: multimodality imaging approach in this exceedingly rare case report

Cor triatriatum and supramitral ring are congenital anomalies which result in formation of three chambers of atria. To the best of our knowledge, simultaneous presence of both entities in the same patient resu...

Authors: Barun Kumar, Ashwin Kodliwadmath, Amar Nath Upadhyay, Anupam Singh, Anshuman Darbari and N. Nanda

The treatment dilemma in adult patients with peripheral pulmonary artery stenosis of diverse etiologies

Peripheral pulmonary artery stenosis (PPAS) is a rare and underdiagnosed phenomenon that is reported infrequently in adult patients. Most patients with PPAS have concomitant congenital heart diseases, a histor...

Authors: Zahra Hosseini, Ata Firouzi, Bahram Mohebbi, Ehsan Khalilipur, Mohammadreza Baay, Kiara Rezaei Kalantari, Iman Harirforoosh and Zahra Khajali

A case report: percutaneous management of high-output heart failure from iatrogenic aortocoronary venous grafting to the coronary sinus

Aortocoronary arteriovenous fistula (ACAVF) due to iatrogenic bypass grafting to a cardiac vein is an exceedingly rare complication resulting from coronary artery bypass grafting (CABG) surgery. If not identif...

Authors: Akarsh Parekh, Vivek Sengupta, Ryan Malek and Mark Zainea

Coronary computed tomography versus coronary angiography for preoperative coronary assessment before valve surgery

Conventional coronary angiography (CAG) is currently the gold standard technique for the assessment of coronary arteries prior to cardiac valve surgery. Although CAG is a relatively safe procedure, however, it...

Authors: Abdalla Elagha, Waleed Khaled, Sahar Gamal, Mohamed Helmy and Ayman Kaddah