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Table 1 Patient characteristics at first clinical ISR presentation

From: In-stent restenosis of drug-eluting stents: clinical presentation and outcomes in a real-world scenario

Parameter

Total (n = 191)

ACS cohort (n = 118)

Non-ACS cohort (n = 73)

P value

Demographics

 Age

61 ± 10

62 ± 10

59 ± 10

0.074

 Men

155 (81.2%)

90 (76.3%)

65 (89.0%)

0.036

 BMI

23.5 ± 3.5

23.7 ± 3.9

23.1 ± 2.7

0.479

Clinical characteristics

 Diabetes

109 (57.1%)

68 (57.6%)

41 (56.2%)

0.881

 Hypertensionƚ

104 (54.5%)

66 (55.9%)

38 (52.1%)

0.655

 Chronic kidney disease

21 (11.0%)

18 (15.3%)

3 (4.1%)

0.017

 Acute kidney injury

32 (16.8%)

24 (20.3%)

8 (11.0%)

0.112

 Dyslipidemia*

98 (67.1%)

55 (63.2%)

43 (72.9%)

0.282

 Current tobacco use

39 (20.4%)

22 (18.6%)

17 (23.3%)

0.464

 CCF

34 (17.8%)

30 (25.4%)

4 (5.5%)

< 0.001

 NYHA 3,4

20 (10.5%)

14 (11.9%)

6 (8.2%)

0.476

 LVEF

53 ± 11

51 ± 10

54 ± 11

0.076

 Previous MI

100 (52.4%)

65 (55.1%)

35 (47.9%)

0.373

 Previous CABG

14 (7.3%)

9 (7.6%)

5 (6.8%)

1.000

 Statin therapy

163 (85.3%)

99 (83.9%)

64 (87.7%)

0.533

Lipid profile* (mg/dL)

 Total cholesterol

145 ± 42

146 ± 45

144 ± 37

0.785

 LDL

80 ± 35

80 ± 38

79 ± 31

0.896

 HDL

39 ± 12

41 ± 13

38 ± 10

0.126

 Triglycerides

130 ± 71

124 ± 67

140 ± 76

0.166

  1. ACS acute coronary syndrome, BMI body mass index, CABG coronary artery bypass grafting, CCF congestive cardiac failure, LVEF left ventricular ejection fraction, LDL low-density lipoprotein, HDL high-density lipoprotein, MI myocardial infarction, NYHA New York Heart Association
  2. *Dyslipidemia defined as total cholesterol > 250 mg/dL, LDL cholesterol > 130 mg/dL, HDL cholesterol < 40 mg/dL (< 50 mg/dL for women) in the fasting state. Data available for 146 patients
  3. ƚBlood pressure > 140/90 mmHg or the use of antihypertensive therapy