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Table 4 Basal characteristics, echocardiographic results, and RV 2DSTE of group 1 subgroups at 20 weeks of receiving chemotherapy

From: Right ventricular 2D speckle-tracking echocardiography in children with osteosarcoma under chemotherapy

 Group 1A (N = 90) (patients with normal RV strain)Group 1B(N = 10) (patients with decreased RV strain)P value
Age, years11.56 ± 1.9914.50 ± 0.520.001*
Male gender, n (%)45 (50.0%)5 (50.0%)1.000
BSA, m21.38 ± 0.071.50 ± 0.010.001*
LVEDD, cm3.62 ± 0.303.60 ± 0.210.789
LVESD, cm1.97 ± 0.571.75 ± 0.260.225
LVEF, %64.13 ± 7.5166.50 ± 1.580.325
LVGLS, %− 23.88 ± 0.86− 23.60 ± 1.220.340
RVGLS, %− 24.22 ± 0.89− 17.40 ± 1.260.001*
Apical RVS, %− 24.90 ± 0.76− 16.40 ± 2.360.001*
Mid RVS, %− 24.21 ± 0.64− 17.01 ± 1.150.001*
Basal RVS, %− 24.61 ± 1.05− 18.20 ± 1.680.001*
Tapse, cm1.85 ± 0.141.67 ± 0.240.044*
FAC, %35.89 ± 0.8835.10 ± 1.190.070
  1. BSA body surface area; LVEDD left ventricular end diastolic dimension; LVESD left ventricular end systolic dimension; LVEF left ventricular ejection fraction; LVGLS left ventricular global longitudinal strain; RVGLS right ventricular global longitudinal strain; Apical, Mid and Basal RVS right ventricular strain; Tapse tricuspid annular plane systolic excursion; FAC fractional area change
  2. * = means significant