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Table 4 Univariate and multivariate logistic regression analysis to identify the significant predictor variables for high adherence to medication

From: Adherence to antihypertensive fixed-dose combination among Egyptian patients presenting with essential hypertension

Parameters

Univariate analysis

Multivariate analysis

OR

95% CI for OR

P value

OR

95% CI for OR

P value

Age

1.007

0.994 to 1.021

0.277

-

-

-

Gender (ref: female)

1.016

0.781 to 1.322

0.906

-

-

-

Race (ref: non-middle eastern)

1.296

0.95 to 1.753

0.092

-

-

-

Education (ref: illiterate)

 Primary/secondary school

1.638

0.950 to 2.824

0.076

1.70

0.998 to 2.896

0.05*

 College/university

2.191

1.270 to 3.778

0.005*

2.354

1.387 to 3.994

0.002*

Marital status (ref: not married)

0.840

0.622 to 1.133

0.253

-

-

-

Employment (ref: non employer)

1.681

1.258 to 2.247

< 0.001*

1.485

1.171 to 1.883

0.001*

Smoking (ref: smoker)

1.416

1.023 to 1.96

0.036*

-

-

-

BMI, Kg/m2

0.974

0.946 to 1.003

0.082

-

-

-

BMI (ref: > 30 Kg/m2)

1.102

0.793 to 1.531

0.562

-

-

-

SBP, mmHg

0.988

0.979 to 0.998

0.016*

0.989

0.980 to 0.998

0.021*

DBP, mmHg

0.983

0.967 to 0.999

0.033*

0.981

0.966 to 0.996

0.015*

HR, beat/min

0.969

0.955 to 0.983

< 0.001*

0.965

0.951 to 0.978

< 0.001*

Duration of HTN

1.004

0.987 to 1.022

0.61

-

-

-

Family history of HTN (ref: no family history)

0.918

0.717 to 1.174

0.493

-

-

-

Antihypertensive treatment (ref: ARBs/HCTZ)

 ACE-I/HCTZ

0.622

0.452 to 0.858

0.114

   

 ACE-I/CCB

0.998

0.652 to 1.528

0.993

   

 ARBs/CCB

0.806

0.567 to 1.145

0.229

   

 ARBs/CCB/HCTZ

0.773

0.526 to 1.136

0.190

-

-

-

 β-blocker/HCTZ

0.732

0.496 to 1.082

0.118

   

 ACEI/thiazide-like diuretic

0.358

0.063 to 2.037

0.247

   

  β-blocker and CCB

1.335

0.178 to 10.008

0.779

   
  1. *statistically significant