Variable | Baseline (n = 50) | After completion of treatment (n = 50) | p value |
---|---|---|---|
Surface ECG | |||
PR interval, ms | 154 ± 25.95 | 151.4 ± 23.82 | 0.124 |
QTc interval, ms | 397.34 ± 29.38 | 395.04 ± 30.23 | 0.403 |
24-h ECG (Holter) monitoring | |||
Minimum heart rate, bpm | 55.88 ± 9.2 | 56.66 ± 9.45 | 0.457 |
Maximum heart rate, bpm | 129.08 ± 20.07 | 128.98 ±16.89 | 0.964 |
Average heart rate, bpm | 79.44 ±10.14 | 79.96 ± 8.77 | 0.534 |
Patients with significant pauses, n (%) | 0 (0%) | 0 (0%) | 1 |
Patients with sinus tachycardia episodes, n (%) | 47 (94%) | 47 (94%) | 1 |
Patients with sinus bradycardia episodes, n (%) | 35 (70%) | 33 (66%) | 0.83 |
Patients with PACs, n (%) | 6 (12%) | 3 (6%) | 0.485 |
Patients with PVCs, n (%) | 22 (44%) | 14 (28%) | 0.145 |