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Table 5 Demographic data and baseline 2D-TTE parameters of the 2 ASD subgroups

From: The changes in biventricular remodelling and function after atrial septal defect device closure and its relation to age of closure

Basic parameters

Group-1 (n = 34)

Group-2 (n = 16)

P value

Age (years)

6.39 ± 0.84

37.66 ± 3.55

< 0.001

Female gender (n (%))

16 (47.1%)

12 (75%)

0.065

Height (m)

1.05 ± 0.04

1.63 ± 0.03

< 0.001

Weight (kg)

23.48 ± 2.74

73.31 ± 3.69

< 0.001

BSA (m2)

0.79 ± 0.06

1.78 ± 0.05

< 0.001

HR (bpm)

104 ± 2.96

81.06 ± 3.23

< 0.001

Mean defect size (cm)

1.18 ± 0.08

2.01 ± 0.15

< 0.001

Mean device size (cm)

1.60 ± 0.10

2.79 ± 0.14

< 0.001

LADi (cm/m2)

3.22 ± 0.12

2.18 ± 0.08

< 0.001

LVEDDi (cm/m2)

4.29 ± 0.16

2.45 ± 0.08

< 0.001

RVEDDi (cm/m2)

3.68 ± 0.19

2.24 ± 0.08

< 0.001

RVEDDi/LVEDDi (cm/m2)

0.87 ± 0.04

0.92 ± 0.03

0.435

TAPSE (cm)

2.61 ± 0.09

3.00 ± 0.16

0.034

RVSP (mmHg)

27.38 ± 1.31

36.68 ± 2.75

0.001

Qp/Qs

2.74 ± 0.22

3.01 ± 0.22

0.462

Septal e′ (cm/s)

11.71 ± 0.36

10.82 ± 0.87

0.270

LVGLS (%)

− 25.87 ± 0.67

− 21.50 ± 0.58

< 0.001

RVGLS (%)

− 26.51 ± 0.84

− 20.38 ± 1.21

< 0.001

RV free wall LS (%)

− 27.45 ± 0.83

− 21.20 ± 1.23

< 0.001

  1. Reported data were presented as mean values ± SEM. P value < 0.05 was considered significant. Independent t test was used for comparison between the groups
  2. Group-1 children and adolescent with ASD, Group-2 adults with ASD, HR heart rate, BSA body surface area, LADi indexed left atrial diameter/BSA, LVEDDi indexed left ventricular end-diastolic diameter/BSA, RVEDDi indexed right ventricular end-diastolic diameter/BSA, Septal e′ early diastolic velocity of septal mitral annulus motion, TAPSE tricuspid annular plane systolic excursion, RVSP right ventricular systolic pressure, Qp/Qs systemic/pulmonary blood flow, LS longitudinal strain, LVGLS left ventricle global longitudinal strain, RVGLS right ventricle longitudinal strain