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Table 3 Predictors of in-hospital mortality in both genders

From: Gender differences in clinical features and complications of infective endocarditis: 11-year experience of a single institute in Egypt

 

Males

Females

Univariate analysis

Survival, n = 182, N (%)

Mortality, n = 61, N (%)

p

Survival, n = 08, N (%)

Mortality, n = 47, N (%)

p

HF NYHA III–IV

27 (14.8)

26 (42.6)

< 0.001

19 (17.6)

19 (40.4)

0.002

Fulminant sepsis

1 (0.5)

14 (23)

< 0.001

1 (0.9)

11 (23.4)

< 0.001

ARF requiring dialysis

4 (3.4)

10 (17.5)

0.002

0 (0)

4 (8.7)

0.015

Poor response to Abs

68 (37.4)

58 (95.1)

< 0.001

42 (38.9)

45 (95.7)

< 0.001

Indication for surgery

125 (68.7)

52 (85.2)

0.012

74 (68.5)

43 (91.5)

0.002

Indicated surgery not performed

33 (26.4)

38 (73.1)

< 0.001

22 (29.7)

25 (58.1)

0.003

Major cerebrovascular emboli

14 (7.7)

12 (19.7)

0.009

14 (13)

10 (21.3)

0.188

Embolization

42 (23.1)

27 (44.3)

0.001

42 (38.9)

22 (46.8)

0.36

HAE

70 (38.5)

35 (57.4)

0.01

51 (47.2)

29 (61.7)

0.097

RHD

45 (24.7)

25 (41)

0.015

48 (44.4)

20 (42.6)

0.83

ICH

8 (4.4)

8 (13.1)

0.017

4 (3.7)

6 (12.8)

0.035

Aortic root abscess

16 (8.8)

5 (8.2)

0.89

4 (3.7)

5 (10.6)

0.09

Mycotic aneurysms

10 (5.5)

3 (4.9)

1.0

5 (4.6)

6 (12.8)

0.09

Pericardial effusion

32 (17.6)

17 (27.9)

0.083

24 (22.2)

12 (25.5)

0.65

Indicated surgery not performed

8.94

3.47–23.04

< 0.001

   
  1. NYHA New York Heart Association, ARF acute renal failure, Abs antibiotics, HAE healthcare-associated endocarditis, RHD rheumatic heart disease, ICH intracranial hemorrhage, OR odds ratio, CI confidence interval