Effects of cardiac pacemakers on left ventricular volumes and function assessed by 3D echocardiography, Doppler method, and global longitudinal strain

Dawood, Moustafa; Elsharkawy, Eman; Abdel-Hay, Mohamed Ayman; Nawar, Moustafa

doi:10.1186/s43044-021-00138-9

The Egyptian Heart Journal

Table 4 Pacing related changes in all the measured parameters at the three time intervals (pre-pacing, at 1 week and 6 months post pacing)

From: Effects of cardiac pacemakers on left ventricular volumes and function assessed by 3D echocardiography, Doppler method, and global longitudinal strain

Measurement	Pre-pacing	Post pacing at 1 week	Post pacing at 6 months	Test	P value
EDV (ml)				Fr
Single-chamber	102.6 ± 25.95	86.81 ± 25.09	88.93 ± 30.39	30.882^*	<0.001^*
Dual-chamber	109.0 ± 22.91	93.43 ± 18.80	97.04 ± 19.62	19.089^*	<0.001^*
Sig. bet. Periods
Single-chamber	p₁<0.001^, p₂=0.002^, p₃=0.338
Dual-chamber	p₁<0.001^, p₂<0.001^, p₃=0.307
ESV (ml)				F
Single-chamber	28.48 ± 9.67	28.96 ± 11.25	36.52 ± 21.87	4.411^*	0.017^*
Dual-chamber	34.43 ± 11.75	34.91 ± 12.24	44.65 ± 15.66	8.077^*	0.001^*
Sig. bet. Periods
Single-chamber	p₁=1.000 , p₂=0.175, p₃=0.040^*
Dual-chamber	p₁=1.000 , p₂=0.018^, p₃=0.004^
SV (ml)				F
Single-chamber	74.07 ± 20.20	57.78 ± 17.47	52.56 ± 17.54	40.039^*	<0.001^*
Dual-chamber	73.7 ± 17.35	58.52 ± 17.02	52.35 ± 13.13	33.559^*	<0.001^*
Sig. bet. Periods
Single-chamber	p₁<0.001^,p₂<0.001^,p₃=0.018^*
Dual-chamber	p₁<0.001^,p₂<0.001^,p₃=0.048^*
HR (bpm)				F
Single-chamber	41.63 ± 8.45	64.04 ± 9.79	62.00 ± 6.45	186.913^*	<0.001^*
Dual-chamber	41.83 ± 9.36	77.96 ± 10.85	76.43 ± 9.43	107.586^*	<0.001^*
Sig. bet. Periods
Single-chamber	p₁<0.001^, p₂<0.001^, p₃=0.325
Dual-chamber	p₁<0.001^, p₂<0.001^, p₃=1.000
COP (L/m)				Fr
Single-chamber	3.07 ± 0.99	3.69 ± 1.13	3.27 ± 1.12	16.020^*	<0.001^*
Dual-chamber	3.04 ± 0.90	4.48 ± 1.14	3.96 ± 1.04	30.776^*	<0.001^*
Sig. bet. Periods
Single-chamber	p₁<0.001^,p₂=0.247,p₃=0.010^
Dual-chamber	p₁<0.001^,p₂=0.002^,p₃=0.027^*
EF (%)				F
Single-chamber	72.41 ± 6.55	65.96 ± 8.41	59.56 ± 9.85	28.566^*	<0.001^*
Dual-chamber	69.35 ± 8.46	60.74 ± 10.62	54.35 ± 10.04	26.749^*	<0.001^*
Sig. bet. periods
Single-chamber	p₁<0.001^,p₂<0.001^,p₃=0.001^*
Dual-chamber	p₁<0.001^,p₂<0.001^,p₃=0.011^*
GLS (%)				F
Single-chamber	-19.41 ± 3.53	-15.44 ± 4.09	-13.52 ± 4.66	62.924^*	<0.001^*
Dual-chamber	-19.65 ± 3.98	-14.52 ± 4.39	-13.13 ± 4.45	50.749^*	<0.001^*
Sig. bet. periods
Single-chamber	p₁<0.001^, p₂<0.001^, p₃<0.001^*
Dual-chamber	p₁<0.001^, p₂<0.001^, p₃=0.001^*

Fr: Friedman test, sig. bet. periods was done using post hoc test (Dunn’s)
F: F test (ANOVA) with repeated measures
p: P value for post hoc test (Bonferroni) for comparison between different periods
p₁: P value for comparing between preoperative and post-operative (7–10 days)
p₂: P value for comparing between preoperative and follow-up after 6 months
p₃: P value for comparing between post-operative (7–10 days) and follow-up after 6 months
^*Statistically significant at P ≤ 0.05

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