|
Parameters
|
Baseline (mean± SD)
|
FU (mean± SD)
|
P value
|
|---|
|
M-Mode LVEF (%)
|
64.6 ± 5.60
|
62.5 ± 6.98
|
0.028
|
|
LVFS (%)
|
35.3 ± 4.83
|
34.12 ± 5.80
|
0.174
|
|
LVDD (cm)
|
4.5 ± 0.53
|
4.61 ± 0.60
|
0.103
|
|
LVSD (cm)
|
2.91 ± 0.40
|
3.54 ± 4.12
|
0.189
|
|
SWT (cm)
|
0.84 ± 0.11
|
0.83 ± 0.11
|
0.584
|
|
PWT (cm)
|
0.9 ± 0.10
|
0.9 ± 0.11
|
0.887
|
|
2D volumes
| | | |
|
LVEDV (ml)
|
62.51±17.10
|
64.7±17.81
|
0.373
|
|
LVESV (ml)
|
23.8±6.93
|
26.2±8.14
|
0.029
|
|
LVEF (%)
|
61.7±5.10
|
60.32±5.60
|
0.115
|
|
Mean delta 2D LVEF (%)
|
− 1.4±7.3
|
|
LAVI (mL/m2)
|
20.24±5.44
|
19.21±4.50
|
0.052
|
|
Diastolic function
| | | |
|
E (cm/s)
|
0.8±0.17
|
1.71±7.9
|
0.323
|
|
A (cm/s)
|
0.65±0.21
|
0.7±0.17
|
0.365
|
|
E/A ratio
|
1.32±0.39
|
1.24±0.39
|
0.049
|
|
EDT (ms)
|
182.14±33.99
|
183.1±23.20
|
0.839
|
|
S TDI MV (cm/s)
|
11.7 ±9.15
|
10.9±1.90
|
0.435
|
|
E’ (cm/s)
|
11.65 ±3.13
|
11.7±3.05
|
0.924
|
|
A’ (cm/s)
|
9.31 ±3.10
|
10.12±2.62
|
0.028
|
|
E/E’ ratio
|
6.96±2.40
|
6.9±2.40
|
0.823
|
|
Tei index
|
0.31±0.10
|
0.34±0.10
|
0.014
|
|
RV function
| | | |
|
TAPSE (cm)
|
2.5±0.49
|
2.8±0.47
|
<0.001
|
|
FAC (%)
|
51.51±7.73
|
51.3±7.90
|
0.808
|
|
PASP mmHg
|
3.44±8.10
|
3.5±8.04
|
0.873
|
|
S-TDI TV (cm/s)
|
13.23 ±2.03
|
13.75±2.02
|
0.027
|
|
RVOT (cm)
|
1.7±0.40
|
1.7±0.32
|
0.570
|
|
CS (cm)
|
0.72±0.15
|
0.73±0.12
|
0.572
|
|
IVC (cm)
|
1.4 ±0.33
|
1.41 ±0.29
|
0.959
|
|
3D Echocardiography
| | | |
|
LVEDV (mL)
|
74.34±15.14
|
75.94 ±18.99
|
0.523
|
|
LVESV (mL)
|
28.13±6.32
|
30.38±9.05
|
0.037
|
|
EF (%)
|
61.84 ±5.79
|
59.88±5.42
|
0.031
|
|
Mean delta 3D LVEF (%)
|
− 2.0 ± 7.4
|
- LVEF left ventricular ejection fraction, LVFS left ventricular fractional shortening, LVDD left ventricular diastolic dimension, LVSD left ventricular systolic dimension, SWT septal wall thickness, PWT posterior wall thickness, 2D 2 dimensional, LVEDV left ventricular end diastolic volumes, LVESV left ventricular end systolic volumes, LAVI left atrium volume indexed, EDT E deceleration time, TDI tissue Doppler imaging, MV mitral valve, RV right ventricle, TAPSE tricuspid annular plane systolic excursion, FAC fractional area change, PASP pulmonary artery systolic pressure, TV tricuspid valve, RVOT right ventricular outflow tract, CS coronary sinus, IVC inferior vena cava
