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Table 5 Comparing patients who had lower versus those who had higher NT-proBNP at the follow-up visit

From: The combined role of NT-proBNP and LV-GLS in the detection of early subtle chemotherapy-induced cardiotoxicity in breast cancer female patients

Variables

Patients with lower FU NT-proBNP (n = 23)

Patients with higher FU NT-proBNP (n = 50)

 

Baseline

FU

p value

Baseline

FU

p value

2D-LVEF

61.3 ± 5.8

62.5 ± 7.1

0.47

61.8 ± 4.7

59.3 ± 4.4

0.012

Mean delta 2D-LVEF

1.2 ± 7.7

− 2.5 ± 6.9

3D-LVEF

60.6 ± 5.6

60.3 ± 6.7

0.87

62.4 ± 5.8

59.0 ± 6.4

0.01

Mean delta 3D-LVEF

− 0.3 ± 8.3

− 2.7 ± 6.9

2D LV-GLS

− 21.0 ± 1.9

− 20.1 ± 1.7

0.055

− 21.7 ± 2.4

− 19.4 ± 2.2

<0.001

Mean delta 2D LV-GLS

− 0.3 ± 0.6

− 2.3 ± 1.8

Median NT-proBNP, (range), pg/ml

37.5 (66.0)

32.1 (62.9)

<0.001

23.7 (446.2)

91.5 (949.5)

<0.001

Median NT-proBNP change (range), pg/ml

− 5.5 (15.6)

46.1 (515.4)

  1. FU follow-up, LVEF left ventricular ejection fraction, GLS global longitudinal strain