Table 4 Association between TGF β1 rs1800469 genotype/alleles and clinical/hematological parameters in study groups
Parameters | Groups | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
CAE patients | Control patients | |||||||||
rs1800469Genotype | rs1800469Alleles | rs1800469Genotype | rs1800469Alleles | |||||||
GG (n=19) | AA (n=12) | GA (n=25) | G Allele (n=44) | A Allele (n=37) | GG (n=16) | AA (n=8) | GA (n=20) | G Allele (n=36) | A Allele (n=28) | |
Age (years) | 64.11±2.17 | 59.58±2.75 | 62.08±1.96 | 62.95±1.44 | 61.27±1.58 | 58.31±3.77 | 64.88±1.87 | 59.30±2.41 | 58.86±2.11 | 60.89±1.85 |
TGF β1 (ng/ml) | 2841.76±361.86 | 3741.11±517.32 | 3360.43±302.65 | 3140.00±232.86 | 3467.50±259.02 | 4914.61±787.63 | 4580.00±757.07 | 4908.57±1121.77 | 4911.48±681.25 | 4810.00±805.69 |
Fasting glucose (mg/dl) | 118.79±7.49 | 127.00±15.28 | 115.84±9.87 | 117.11±6.41 | 119.46±8.23 | 129.44±16.30 | 97.13±6.45 | 131.25±18.17 | 130.44±12.25 | 121.50±13.34 |
HbA1c (%) | 6.35±0.19 | 6.82±0.69 | 6.47±0.19 | 6.42±0.13 | 6.58±0.25 | 6.30±0.29 | 5.85±0.169 | 6.17±0.18 | 6.23±0.16 | 6.08±0.13 |
ALT (U/L) | 24.42±7.56 | 22.33±3.00 | 32.16±5.11 | 28.82±4.35 | 28.97±3.62 | 23.88±5.33 | 23.25±4.34 | 21.15±2.28 | 22.36±2.65 | 21.75±2.01 |
AST (U/L) | 22.21±4.67 | 20.08±1.92 | 27.96±3.51 | 25.48 ±2.83 | 25.41±2.50 | 23.69±5.04 | 22.63±1.94 | 19.75±1.20 | 21.50 ±2.32 | 20.57±1.03 |
BUN (mg/dl) | 15.84±0.89 | 15.00±1.10 | 16.20 ±0.80 | 16.05 ±0.59 | 15.81±0.64 | 18.50±2.36 | 17.38±1.72 | 15.25±0.94 | 16.69 ±1.18 | 15.86±0.83 |
Creatine (mg/dl) | 0.81±0.03 | 0.99±0.09 | 0.97±0.05 | 0.90 ±0.03 | 0.97±0.04 | 0.94±0.06 | 0.84±0.11 | 0.81 ±0.05 | 0.87 ±0.04 | 0.82±0.04 |
WBC (103μl) | 8.18 ±0.45 | 8.00±0.72 | 8.86±0.62 | 8.57 ±0.40 | 8.58 ±0.48 | 7.59 ±0.61 | 7.54±0.98 | 8.37 ±0.54 | 8.02 ±0.41 | 8.13 ±0.47 |
Platelet (103μl) | 249.16±16.25 | 212.17 ±22.71 | 244.76±12.12 | 246.66±9.72 | 234.19 ±11.12 | 245.44 ±17.70 | 257.50 ±26.22 | 250.55 ±15.69 | 248.27 ±11.58 | 252.54±13.23 |