Safety and efficacy outcomes at 1 year after MitraClip therapy for percutaneous mitral valve repair in patients with severe mitral regurgitation: the Egyptian experience

The Egyptian Heart Journal

Table 6 Follow up of the mitral regurgitation grade, NYHA class, ejection fraction, and the left atrium

		Pre-operative	1 month	6 months	1 year	Test statistic	P value	Post hoc analysis
MR grade	Median (IQR)	4.0 (4.0-4.0)	2.0 (1.5-2.0)	2.0 (2.0-2.0)	2.0 (2.0-2.0)	54.190	<0.001*	P1<0.001^a P2<0.001 ^a P3<0.001 ^a	P4=0.083 P5=0.083 P6>0.999
NYHA class	Median (IQR)	3.0 (3.0-3.5)	1.0 (1.0-2.0)	1.0 (1.0-1.5)	1.0 (1.0-1.0)	56.302	<0.001*	P1<0.001 ^a P2<0.001 ^a P3<0.001 ^a	P4=0.157 P5=0.083 P6=0.317
EF	Mean± SD	53.8 ±7.8	58.8 ±8.4	62.0 ±6.6	62.8± 6.2	22.872	<0.001*	P1=0.002 ^a P2<0.001 ^a P3<0.001 ^a	P4=0.104 P5=0.024 P6=0.279
LA	Mean± SD	44.9±3.2	43±2.2	43±2.3	43±2.1	2.8	0.04	P1=0.009 P2=0.011 P3=0.011	P4=1.0 P5=0.88 P6=0.88

P1 Pre versus 1 month, P2 Pre versus 6 months, P3 Pre versus 1 year, P4 1 Month versus 6 months, P5 1 Month versus 1 year, P6 6 Months versus 1 year, SD Standard deviation, MR Mitral regurgitation, EF Ejection fraction, LA Left atrium, NYHA New York Heart Association
P^a was adjusted for multiple comparisons (Bonferroni correction) resulting in a significant level at P<0.008
*Significant at P <0.05