Efficacy and safety of hydro-mechanical defragmentation in intermediate- and high-risk pulmonary embolism

The Egyptian Heart Journal

Table 3 Rate of change in efficacy parameters of the study groups subtracting the previous value from the follow-up results

The rate of change^a	Group A (HMD)	Group B (ST)	p value
The rate of change^a	No. 25	No. 25	p value
Increase in SBP
After 24 h	12.08 ± 9.32	9.6 ± 4.55	0.239
After 48 h	20.87 ± 13.11	12.27 ± 5.28	0.007**
After 30 day	32 ± 16.73	26.84 ± 9.46	0.247
Increase in DBP
After 24 h	11.25 ± 11.54	6 ± 6.45	0.054
After 48 h	15.22 ± 12.75	8.18 ± 5.88	0.023*
After 30 day	23 ± 16.25	18.16 ± 9.01	0.261
Decrease in PASP
After 48 h	13.89 ± 8.05	1.53 ± 2.29	< 0.001**
After 30 day	20.41 ± 7.13	8.18 ± 3.32	< 0.001**
Decrease in respiratory rate
After 24 h	6.88 ± 2.79	5.24 ± 4.7	0.147
After 48 h	10.71 ± 5	6.45 ± 5.47	0.008**
After 30 day	17.5 ± 4.37	14.24 ± 6.19	0.069
Increase in oxygen saturation
After 24 h	3.58 ± 2.5	0.68 ± 1.31	< 0.001**
After 48 h	4.74 ± 2.8	1.18 ± 1.59	< 0.001**
After 30 day	6.35 ± 2.83	2.83 ± 1.2	< 0.001**
Decrease in heart rate
After 24 h	13.48 ± 9.82	9.2 ± 6.4	0.078
After 48 h	21.82 ± 10.53	13.64 ± 9.02	0.008**
After 30 day	35.5 ± 10.99	30.44 ± 9.88	0.146

Data are presented as mean ± standard deviation. HMD = hydro-mechanical defragmentation; ST = systemic thrombolysis; PE = pulmonary embolism; SBP = systolic blood pressure; DBP = diastolic blood pressure; PASP = pulmonary artery systolic pressure
*Statistically significant difference (p < 0.05); **Highly statistically significant difference (p < 0.01). ^aThe change is measured by subtracting the previous value to calculate the rate of change in each efficacy parameter