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Table 1 Baseline measurements of included patients with COVID-19 according to level of NT-proBNP

From: Optimal cut points of N-terminal of the prohormone brain natriuretic peptide (NT-proBNP) in patients with COVID-19

Measures

Total

Low

NT-proBNP ≤ 331

Medium

NT-331 < NT-proBNP ≤ 11,126

High

NT-proBNP > 11,126

P value

Age (year)

61.69 (17.41)

53.68 (17.45)

64.06a (16.22)

61.31 (19.53)

0.001

Gender (F/M)

127/145

22/27

82/95

23/23

0.87

ICU admission (yes/no)

138/134

18/31

89/88

31/15a,b

0.01

severity (severe/non-severe)

168/104

22/27

110/67a

36/10a,b

0.004

Hospital death (yes/no)

80/188

4/44

54/121a

22/23a,b

< 0.0001

History of HT (yes/no)

136/136

18/31

91/86

27/19

0.08

History of CAD (yes/no)

60/212

7/42

37/140

16/30

0.045

History of DM (yes/no)

72/200

12/37

48/129

12/34

0.93

History of resp (yes/no)

17/255

3/46

12/165

2/44

0.83

History of cancer (yes/no)

14/258

4/45

8/169

2/44

0.57

History of KD (yes/no)

16/256

2/47

11/166

3/43

0.84

History of ARB yes/no

112/160

16/33

74/103

22/24

0.31

WBC (103/µL)

10.38 (5.61)

8.46 (4.8)

10.61 (5.99)

11.55a (4.34)

0.02

CRP (mg/L)

100.61 (115.22)

74.89 (69.57)

108.16 (132.30)

97.47 (65.88)

0.21

BUN (mg/dL)

34.85 (30.55)

23.72 (25.03)

34.30 (27.20)

50.46a,b (42.17)

0.0001

PCT (ng/mL)

3.28 (11.28)

0.90 (2.54)

2.85 (10.42)

6.79 (16.81)

0.09

Creatinine (mg/dL)

1.57 (1.47)

1.11 (1.10)

1.50 (1.14)

2.42a,b (2.43)

0.0001

Troponin (positive/negative)

64/205

0/49

25/105a

39/7a,b

< 0.0001

NT-proBNP (pg/mL)

6362.17 (9013.81)

131.02 (113.99)

3516.54a (2838.85)

23,949.17a,b (8213.34)

< 0.0001

  1. HT Hypertension, CAD Coronary Artery Disease, DM Diabetes Mellitus, Resp Respiratory Disease, KD kidney Disease, ARB Angiotensin II Receptor Blockers, WBC White Blood Cell, CRP C-reactive protein, BUN Blood Urea Nitrogen, PCT Procalcitonin, NT-proBNP N-terminal pro-brain natriuretic peptide
  2. aSignificant in comparison with low
  3. bSignificant in comparison with medium