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Table 5 GO analysis for whole targeted genes (n = 13) by miR-194-5p and miR-454-3p using STRING tool

From: miR-454-3p and miR-194-5p targeting cardiac sarcolemma ion exchange transcripts are potential noninvasive diagnostic biomarkers for childhood dilated cardiomyopathy in Egyptian patients

GO

FDR*

Cellular components (CC)

Sarcolemma

2.11e-0.6

T-tubule

0.00052

Ca channel complex

0.00058

Molecular function (MF)

 Alpha actinin binding

0.0014

 Sod–pot exchange

0.0064

Biological process (BP)

 Cell communication by electric coupling involved in cardiac contraction

4.19e-05

 Ca ion transport

0.00069

Relevant pathway prioritization

KEEG pathway

 DCM

1.4e-10

 HCM

1.4e-10

 Arrhythmogenic RV cardiomyopathy

8.98e-09

 Cardiac muscle contraction

1.29e-08

Reactome pathway

 Muscle contraction

9.56e-05

 Cardiac conduction

0.0011

Wiki pathway

 Arrhythmogenic RV cardiomyopathy

9.13e-08

 Ca regulation in cardiac cell

0.0214

  1. *FDR; False Detection Rate