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Table 2 QRS interval values before each trastuzumab/trastuzumab emtansine application and 6 months after the last cycle

From: Effects of trastuzumab and trastuzumab emtansine on corrected QT interval and left ventricular ejection fraction in patients with metastatic (HER2+) breast cancer

Number of cycle

TRASTUZUMAB

TRASTUZUMAB EMTANSINE

QRS interval mean values (mean ± SD) (ms)

QRS interval values (ms)

QRS1

100.8 ± 11.16

99.4 ± 7.07

QRS2

100.8 ± 10.36

99.4 ± 6.75

QRS3

101.2 ± 10.23

99.8 ± 6.45

QRS4

101.6 ± 10.25

100.3 ± 6.58

QRS5

101.7 ± 10.15

100.4 ± 6.69

QRS6

101.6 ± 10.21

100.4 ± 6.71

QRS7 (after 6 months)

101.4 ± 10.30

100.1 ± 6.78

  1. QRS interval values showed no statistically significant difference between trastuzumab/trastuzumab emtansine cycle. The same was found six months after the last application