Table 2 The distrubitions of CYP2D6*2, CYP2D6*3, CYP2D6*4 and CYP2D6 *10 alleles in patient and control group
Patient cohort (%) | Control cohort (%) | Total (%) | ||
|---|---|---|---|---|
CYP2D6*2 | ||||
wt/wt | 56 (39.4) | 86 (60.6) | 142 (100) | p = 0.001 |
wt/*2 | 31 (68.9) | 14 (31.1) | 45 (100) | |
*2/*2 | 0 (0) | 0 (0) | 0 (0) | |
CYP2D6*3 | ||||
wt/wt | 61 (44.9) | 75 (55.1) | 136 (100) | p = 0.454 |
wt/*3 | 26 (51) | 25 (49) | 51 (100) | |
*3/*3 | 0 (0) | 0 (0) | 0 (0) | |
CYP2D6*4 | ||||
wt/wt | 62 (42.8) | 83 (57.2) | 145 (100) | p = 0.055 |
wt/*4 | 25 (59.5) | 17 (40.5) | 42 (100) | |
*4/*4 | 0 (0) | 0 (0) | 0 (0) | |
CYP2D6*10 | ||||
wt/wt | 78 (53.4) | 68 (46.6) | 146 (100) | p = 0.0001 |
wt/*10 | 9 (22) | 32 (78) | 41(100) | |
*10/*10 | 0 (0) | 0 (0) | 0 (0) |