Table 3 The status of rate control with diltiazem in the presence of polymorphism in *2, *3, *4 and *10 alleles and their statistical association
Adequate rate control after one or two doses of diltiazem (%) | Inadequate rate control after one or two doses of diltiazem (%) | Total (%) | |||
|---|---|---|---|---|---|
*2 | wt/wt | 40 (71.4) | 16 (28.6) | 56 (100) | p* = 0.003 |
wt/*2 | 12 (38.7) | 19 (61.3) | 31 (100) | ||
*3 | wt/wt | 39 (63.9) | 22 (36.1) | 61 (100) | p* = 0.225 |
wt/*3 | 13 (50) | 13 (50) | 26 (100) | ||
*4 | wt/wt | 47 (75.8) | 15 (24.2) | 62 (100) | p* = 0.0001 |
wt/*4 | 5 (20) | 20 (80) | 25 (100) | ||
*10 | wt/wt | 52 (66.7) | 26 (33.3) | 78 (100) | p** = 0.0001 |
wt/*10 | 0 (0.0) | 9 (100) | 9 (100) |