Predictive value of CHA2DS2VASC score for contrast-induced nephropathy after primary percutaneous coronary intervention for patients presenting with acute ST-segment elevation myocardial infarction

The Egyptian Heart Journal

Table 3 Univariate and multivariate regression analysis for CAHADSVASC-, Mehran’s score components and CMV/eGFR ratio to predict CIN

	Univariate regression analysis		Multivariate regression analysis
	OR (95% CI)	P value	OR (95% CI)	P value
CHF	4.49 (2.14–9.45)	< 0.001	4.32 (1.58–11.81)	0.004
Hypertension	0.25 (0.029– 2.18)	0.211	–	–
Diabetes	2.74 (1.37–5.5)	0.014	3.1 (1.29–7.48)	0.012
Age from 65 to 74 years	23.97 (10.63–54.05)	< 0.001	61.07 (19.38–192.47)	< 0.001
Age ≥ 75 years	11.87 (3.03–46.44)	< 0.001	–	–
Female gender	1.76 (0.77–4.04)	0.182	–	–
Stroke/TIA	15.33 (4.21–55.89)	< 0.001	92.52 (15.55–550.64)	< 0.001
Hypotension	26.86 (10.62–68.06)	< 0.001	85.34 (11.41–637.9)	< 0.001
CHF	4.49 (2.14–9.45)	< 0.001	59 (61.98—5044)	< 0.001
Age ≥ 75 years	11.87 (3.03–46.44)	< 0.001	–	–
Diabetes	2.47 (1.2–5.09)	0.014	–	–
CMV (≥ 3)	8.72 (3.74–20.36)	< 0.001	1.06 (1.04–1.09)	< 0.001
CMV (mL)	1.03 (1.02–1.04)	< 0.001	1.01 (0.99–1.02)	0.053
CMV/eGFR ratio	3.42 (2.89–5.11)	< 0.001	2.45 (1.49–4.03)	< 0.001

95% CI, 95% confidence interval; CHF, congestive heart failure or reduced left ventricular ejection fraction, CMV, contrast media volume; eGFR, estimated GFR (by MDRD-4); OR, odds ratio; TIA, transient ischemic attack