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Table 2 Comparison of NYHA, EF, blood pressure, treatment, and laboratory findings between patients with and without AKI

From: The prognostic role of urea-to-creatinine ratio in patients with acute heart failure syndrome: a case–control study

Parameter

Non-AKI (n = 30)

AKI (n = 30)

P value

NYHA class D1

 1

0 (0.0%)

0 (0.0%)

0.046

 2

0 (0.0%)

1 (3.3%)

 3

12 (40.0%)

4 (13.3%)

 4

18 (60.0%)

25 (83.3%)

NYHA class D2

 1

1 (3.3%)

2 (6.7%)

0.014

 2

15 (50.0%)

6 (20.0%)

 3

13 (43.3%)

13 (43.3%)

 4

1 (3.3%)

9 (30.0%)

NYHA class D3

  1

6 (20.0%)

5 (16.7%)

0.017

   2

21 (70.0%)

12 (40.0%)

   3

3 (10.0%)

7 (23.3%)

   4

0 (0.0%)

6 (20.0%)

SBP*

110.0 (60–210)

100.0 (60–200)

0.026

DBP*

70.0 (30–110)

60.0 (40–100)

0.032

EF*

40.0 (18–55)

38.5 (19–55)

0.486

Length of stay in hospital*

4.5 (3–18)

8.5 (3–29)

 < 0.001

Treatment

 ACEIS

27 (90.0%)

9 (30.0%)

 < 0.001

 BB

24 (80.0%)

16 (53.3%)

0.028

 MRA

26 (86.7%)

10 (33.3%)

 < 0.001

 Diuretics

30 (100.0%)

29 (96.7%)

1.00

 Inotropics

8 (26.7%)

12 (40.0%)

0.273

 Vasopressors

1 (3.3%)

12 (40.0%)

0.001

 HCT*

35.5 ± 5.7

34.1 ± 6.3

0.373

 Creatinine (first reading)

1.3 (0.7–2.9)

2.5 (0.7–5.9)

 < 0.001

 Creatinine (second reading)

1.3 (1.0–3.0)

3.0 (2.0–6.0)

 < 0.001

 Creatinine (third reading)

1.1 (0.8–1.9)

2.8 (0.9–5.8)

 < 0.001

 Urea (first reading)

43.5 (22–88)

98.0 (31–210)

 < 0.001

 Urea (second reading)

46.5 (28–157)

136.5 (20–280)

 < 0.001

 Urea (third reading)

38.0 (21–95)

100.0 (30–290)

 < 0.001

 BUN (first reading)

21.0 (10.2–65.4)

45.7 (14.4–98.0)

 < 0.001

 BUN (second reading)

21.5 (13–73)

63.5 (19–130)

 < 0.001

 BUN (third reading)

17.4 (10.5–44.3)

46.0 (14–135.5)

 < 0.001

 BUN/Cr (first reading)

15.4 (10.5–41.4)

21.1 (7.7–37.0)

0.013

 BUN/Cr (second reading)

15.0 (10–27)

17.0 (8.0–37)

0.048

 BUN/Cr (third reading)

14.9 (11.6–26.2)

19.5 (4.7–32.3)

0.046

 GFR (first reading)

76.8 (28.1–144)

34.4 (14.1–167.0)

 < 0.001

 GFR (second reading)

66.0 (24–123)

30.0 (12–73)

 < 0.001

 GFR (third reading)

83.0 (36–115)

30.5 (10.1–110.2)

 < 0.001

 Albumin

3.9 (3.0–4.8)

3.8 (1.2–4.5)

0.047

 INR

1.0 (1.0–2.0)

1.0 (1.0–3.0)

0.113

 Na

124.0 (120–128)

123.5 (120–128)

0.759

 K

4.0 (2.9–6.0)

5.0 (3.0–6.0)

0.016

  1. Data are presented as mean ± SD, median (Min–Max), and frequency (%). P < 0.05 is considered significant. Glomerular filtration rate: GFR, BUN: Blood urea nitrogen, Cr: Creatinine, Na: Sodium, K: Potassium, INR: International normalized ratio
  2. *Statistically significant, independent predictor