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Table 4 Comparison of laboratory parameters among patient group regarding presence and absence of AKI with low or high BUN/Cr

From: The prognostic role of urea-to-creatinine ratio in patients with acute heart failure syndrome: a case–control study

Parameter

Group 1 (n = 25)

Group 2 (n = 5)

Group 3 (n = 14)

Group 4 (n = 16)

P value

Hb*

12.5 ± 2.22

12.1 ± 2.23

11.9 ± 3.38

11.8 ± 1.72

0.816

HCT*

35.7 ± 5.69

34.6 ± 6.65

34.14 ± 8.37

34.13 ± 4.03

0.821

Creatinine (1st reading)

1.3 (0.8–2.9)

1.2 (0.7–2.3)

2.8 (0.7–5.9)

2.1 (1.3–4.3)

P = 0.058

P2 = 0.026

P3 ≤ 0.001

P5 = 0.025

Creatinine (2nd reading)

1.0 (1.0–2.0)

2.0 (1.0–3.0)

3.5 (2.0–6.0)

3.0 (2.0–6.0)

P ≤ 0.001

P2 ≤ 0.001

P3 ≤ 0.001

P4 = 0.034

P5 = 0.015

Creatinine (3rd reading)

1.1 (0.9–1.8)

1.6 (0.8–1.9)

2.6 (0.9–5.1)

3.05 (1.2–5.8)

P = 0.004

P2 = 0.001

P3 ≤ 0.001

P5 = 0.008

Urea (1st reading)

42.0 (22–70)

48.0 (28.1–88)

90.0 (31–170)

115.0 (68–210)

P = 0.019

P2 = 0.006

P3 ≤ 0.001

P5 ≤ 0.001

P6 = 0.017

Urea (2nd reading)

44.0 (28–82)

85.0 (38.0–157.0)

93.5 (41–195)

150.0 (20–280)

P ≤ 0.001

P1 = 0.013

P2 ≤ 0.001

P3 ≤ 0.001

P5 = 0.050

P6 = 0.007

Urea (3rd reading)

35.0 (21–67)

70.0 (37–95)

74.0 (30–140)

155.0 (52–290)

P = 0.003

P1 = 0.004

P2 = 0.005

P3 ≤ 0.001

P5 = 0.004

P6 = 0.001

BUN (1st reading)

20.0 (10.2–32.7)

37.3 (14–65.4)

42.0 (14.4–79.0)

53.5 (32.0–98.0)

P = 0.013

P2 = 0.006

P3 ≤ 0.001

P5 = 0.019

P6 = 0.017

BUN (2nd reading)

20.0 (13–32)

40.0 (18–73)

43.5 (19–91)

70.0 (36–130)

P ≤ 0.001

P1 = 0.013

P2 ≤ 0.001

P3 ≤ 0.001

P5 = 0.015

P6 = 0.002

BUN (3rd reading)

16.3 (10.5–31.3)

32.0 (17.2–44.3)

34.5 (14–65)

72 (22.5–135.5)

P = 0.002

P1 = 0.003

P2 = 0.005

P3 ≤ 0.001

P5 = 0.004

P6 = 0.001

BUN/Cr (1st reading)

15.0 (10.5–19.6)

24.0 (18.6–41.4)

13.6 (7.7–26.0)

23.7 (15.5–37.0)

P = 0.005

P1 ≤ 0.001

P3 ≤ 0.001

P4 = 0.007

P6 ≤ 0.001

BUN/Cr (2nd reading)

15.0 (10.0–20.0)

21.0 (17.0–27.0)

12.5 (8.0–18.0)

23.5 (15.0–37.0)

P ≤ 0.001

P1 ≤ 0.001

P3 ≤ 0.001

P4 ≤ 0.001

P6 ≤ 0.001

BUN/Cr (3rd reading)

14.3 (11.6–24.1)

21.5 (18.4–26.2)

13.9 (4.7–17.1)

22.1 (18.5–32.3)

P = 0.002

P1 ≤ 0.001

P3 ≤ 0.001

P4 ≤ 0.001

P6 ≤ 0.001

GFR (1st reading)

76.7 (29.3–127.0)

104.0 (28.1–144)

29.0 (15–167)

40.5 (14.1–102)

P = 0.041

P2 = 0.017

P3 ≤ 0.001

P5 = 0.025

GFR (2nd reading)

66.0 (37–115)

52.0 (24–123)

25.0 (14–68)

31.0 (12–73)

P = 0.001

P2 ≤ 0.001

P3 ≤ 0.001

P5 = 0.032

GFR (3rd reading)

82.0 (47.5–115)

85.0 (36.0–114)

32.5 (17.1–106)

27.0 (10.1–110.2)

P = 0.005

P2 = 0.001

P3 ≤ 0.001

P4 = 0.044

P5 = 0.015

Albumin

3.9 (3–4.8)

3.8 (3.2–4.5)

3.8 (1.2–4.5)

3.5 (2.9–4.1)

P = 0.619

P3 = 0.017

INR

1.0 (1–2)

1.0 (1–2)

1.0 (1–2)

1.0 (1–3)

0.278

Na

124.0 (120–128)

124.0 (120–128)

123.5 (120–126)

123.5 (120–128)

0.940

K

4.0 (2.9–6.0)

4.0 (4–6)

5.0 (4–6)

4.5 (3–6)

P = 0.009

P2 = 0.008

  1. Data are presented as mean ± SD, median (Min–Max), and frequency (%). P < 0.05 is considered significant. GFR: Glomerular filtration rate, K: Potassium, Cr: Creatinine, Na: Sodium, BUN: Blood urea nitrogen, INR: International normalized ratio
  2. *Statistically significant, independent predictor