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Table 2 Echocardiographic variables of the patients studied

From: Impact of diastolic pulmonary gradient and pulmonary vascular remodeling on survival after left ventricular assist device implantation and heart transplantation

Variables

All patients (n = 73)

Pre-VAD DPG < 7 (n = 49, 67.1%)

Pre-VAD DPG ≥ 7 (n = 24, 32.9%)

P value

Pre-LVAD echocardiography

 LV-EDV (ml)

241.4 (189.2–299.8)

218.9 (180–273)

265.45 (196.7–384.05)

0.04

 LV-ESV (ml)

191.8 (140–247.4)

172.9 (136.3–236.8)

211.9 (161.65–315.75)

0.047

 LV-EF (%)

20.2 (14–25.7)

20.5 (14.4–26.8)

19.05 (12.95–25.2)

0.46

 LA diameter (cm)

5.1 (4.5–5.4)

4.7 (4.4–5.4)

5.3 (4.9–5.95)

0.27

 Cardiac output (L/min)

3.7 (2.89–4.3)

3.7 (2.85–4.3)

3.9 (2.89–4.5)

0.622

 Cardiac index (L/min per m2)

1.89 (1.52–2.3)

1.88 (1.56–2.35)

1.9 (1.45–2.3)

0.9

 Estimated PASP (mmHg)

55 (45–60)

50 (44–63)

68 (58–76)

 < 0.001

Mitral regurgitation (n, %)

 No MR

0

0

0

0.08

 Mild MR

14 (19.2)

11 (22.4)

3 (12.5)

 

 Moderate MR

33 (45.2)

25 (51)

8 (33.3)

 

 Severe MR

26 (35.6)

13 (26.5)

13 (54.2)

 

Tricuspid regurgitation (n, %)

 No TR

0

0

0

0.24

 Mild TR

14 (19.2)

12 (24.5)

2 (8.3)

 

 Moderate TR

32 (43.8)

21 (42.9)

11 (45.8)

 

 Severe TR

27 (37)

16 (32.7)

11 (45.8)

 

Aortic regurgitation (n, %)

 No AR

57 (78.1)

40 (81.6)

17 (70.8)

0.29

 Mild AR

16 (21.9)

9 (18.4)

7 (29.2)

 

Post-LVAD echocardiography

 LV-EDV (ml)

174.75 (120.5–211.5)

161.35 (106.05–193.9)

210.45 (151.45–243.7)

0.002

 LV-ESV (ml)

128.6 (86.4–167.7)

110.9 (71.4–154.5)

155.3 (120.75–188.05)

0.005

 LV-EF (%)

23.4 (18.1–30.8)

25 (20–35.8)

20.7 (15–23.9)

0.03

 LA diameter (cm)

4.5 (4.3–5)

4.5 (4.2–4.8)

4.8 (4.4–5.2)

0.04

 Estimated PASP (mmHg)

35 (30–42.5)

35 (30–40)

40 (35–50)

0.041

Mitral regurgitation (n, %)

 No MR

8 (10.9)

6 (12.2)

2 (8.3)

0.005

 Mild MR

53 (72.6)

40 (81.6)

13 (54.2)

 

 Moderate MR

11 (15.1)

3 (6.1)

8 (33.3)

 

 Severe MR

1 (1.4)

0

1 (4.2)

 

Tricuspid regurgitation (n, %)

 No TR

1 (1.4)

0

1 (4.2)

0.014

 Mild TR

48 (65.8)

36 (73.5)

12 (50)

 

 Moderate TR

16 (21.9)

11 (22.4)

5 (20.8)

 

 Severe TR

8 (11)

2 (4.1)

6 (25)

 

Aortic regurgitation (n, %)

 No AR

49 (67.1)

35 (71.4)

14 (58.3)

0.45

 Mild AR

23 (31.5)

13 (26.5)

10 (41.7)

 

 Moderate AR

1 (1.4)

1 (2)

0

 
  1. Data were presented as median with the 25th and 75th interquartiles or count with frequency
  2. LV-EDV left ventricular end diastolic volume, LV-ESV left ventricular end systolic volume, LV-EF left ventricular ejection fraction, LA left atrium, PASP pulmonary artery systolic pressure, MR mitral regurgitation, AR aortic regurgitation, TR tricuspid regurgitation