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Table 6 Risks of mortality according to pulmonary hemodynamics

From: Impact of diastolic pulmonary gradient and pulmonary vascular remodeling on survival after left ventricular assist device implantation and heart transplantation

Variables

HR

95% CI

P value

Pre-LVAD DPG ≥ 7 mmHg

 Crude

2.048

1.28–4.518

0.036

 Adjusted

1.83

1.21–6.341

0.039

Pre-LVAD TPG ≥ 12 mmHg

1.321

0.583–2.992

0.505

Pre-LVAD PVR ≥ 3 WU

2.35

0.803–6.848

0.119

Pre-LVAD PVR ≥ 2 WU

1.61

0.62–5.17

0.42

Post-LVAD DPG ≥ 7 mmHg

 Crude

4.243

1.561–11.538

0.005

 Adjusted

3.824

1.482–14.648

0.002

Post-LVAD TPG ≥ 12 mmHg

1.91

0.841–4.338

0.122

Post-LVAD PVR ≥ 3 WU

 Crude

2.56

1.117–5.848

0.026

 Adjusted

2.37

1.241–7.254

0.038

Pre-LVAD PVR ≥ 2 WU

1.74

0.97–6.12

0.057

Pre-transplantation DPG ≥ 7 mmHg

1.94

0.22–16.75

0.548

Pre-transplantation TPG ≥ 12 mmHg

1.174

0.215–6.42

0.85

Pre-transplantation PVR ≥ 3 WU

1.937

0.22–16.747

0.55

Pre-transplantation PVR ≥ 2 WU

1.31

0.21–8.37

0.58

Post-transplantation DPG ≥ 7 mmHg (T3)

4.16

0.37–46.68

0.25

Post-transplantation TPG ≥ 12 mmHg (T3)

6.35

0.358–112.8

0.21

Post-transplantation PVR ≥ 3 WU (T3)

8.12

0.49–134.1

0.14

Post-transplantation DPG ≥ 7 mmHg (T6)

0.033

0.001–495.2

0.64

Post-transplantation TPG ≥ 12 mmHg (T6)

0.039

0.001–219.85

0.722

Post-transplantation PVR ≥ 3 WU (T6)

0.044

0.000–1639.42

0.844

Post-transplantation DPG ≥ 7 mmHg (T12)

0.04

0.000–6575.52

0.77

Post-transplantation TPG ≥ 12 mmHg (T12)

0.04

0.000–1659.4

0.84

Post-transplantation PVR ≥ 3 WU (T12)

0.04

0.000–1659.4

0.84

  1. Pre-transplantation variables are the post-LVAD variables in patients who underwent heart transplantation. Adjustment of HR was done for age, gender, atrial fibrillation, CRT, BMI and mitral regurgitation